SAB4500638

Anti-DDX5 antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): DEAD-box protein 5, DEAD-box protein p68, HELR, HLR1, Probable RNA-dependent helicase p68
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 69 kDa
• reatividade de espécies: mouse, rat, human
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:1000; immunofluorescence: 1:100-1:500
• nº de adesão NCBI: P17844
• nº de adesão UniProt: P17844
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... DDX5(1655)

Descrição

Descrição geral

Anti-DDX5 Antibody detects endogenous levels of total DDX5 protein.

DDX5 (DEAD, Asp-Glu-Ala-Asp, box helicase 5) is a multifunctional protein belonging to the DEAD box family of RNA helicases. It consists of twelve conserved motifs (including the signature D-E-A-D motif) forming a conserved ′helicase′ central domain, which plays an important role in the RNA metabolism.

Imunogênio

The antiserum was produced against synthesized peptide derived from human DDX5/DEAD-box Protein 5.

Immunogen Range: 565-614

Aplicação

Anti-DDX5, C-Terminal antibody produced in rabbit is suitable for indirect immunofluorescence and indirect ELISA.

Ações bioquímicas/fisiológicas

DDX5 (DEAD, Asp-Glu-Ala-Asp, box helicase 5) is associated with the regulation of pre-mRNA splicing mechanism. It acts as a transcriptional coactivator to control alternative splicing during the formation of spliceosome. DDX5 provides stability to the RNA secondary structure during several activities such as in the translation initiation, nuclear and mitochondrial splicing. It facilitates the unwinding as well as detachment of protein part from RNA. The protein also participates in the estrogen- and androgen-signaling pathway.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable