SAB4300140

Anti-phospho-PRKCQ (pSer⁶⁹⁵) antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Anti-MGC126514 antibody produced in rabbit, Anti-MGC141919 antibody produced in rabbit, Anti-PRKCT antibody produced in rabbit, Anti-nPKC-theta antibody produced in rabbit, Anti-protein kinase C, theta antibody produced in rabbit
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: ~80 kDa
• reatividade de espécies: human
• concentração: 1 mg/mL
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
• Isotipo: IgG
• sequência de imunogênio: (N-F-SP-F-M)
• nº de adesão NCBI: NP_006248.1
• nº de adesão UniProt: Q04759
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pSer695)
• Informações sobre genes: human ... PRKCQ(5588)

Descrição

Imunogênio

Peptide sequence around phosphorylation site of serine 695 (N-F-S(p)-F-M), according to the protein PRKCQ.

Características e benefícios

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Descrição-alvo

This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. Ref.8 PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.

forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable