SAB4300097

Anti-phospho-CDC25C (pSer²¹⁶) antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Anti-CDC25 antibody produced in rabbit, Anti-cell division cycle 25 homolog C (S. pombe) antibody produced in rabbit
• Número MDL: MFCD00802890
• Código UNSPSC: 12352203
• NACRES: NA.43

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: ~60 kDa
• reatividade de espécies: human
• concentração: 1 mg/mL
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200
• Isotipo: IgG
• sequência de imunogênio: (S-P-SP-M-P)
• nº de adesão NCBI: NP_001781.2
• nº de adesão UniProt: P30307
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pSer216)
• Informações sobre genes: human ... CDC25C(995)

Descrição

Imunogênio

Peptide sequence around phosphorylation site of serine 216 (S-P-S(p)-M-P), according to the protein CDC25C.

Características e benefícios

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Descrição-alvo

cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encodedprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclinB-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiplealternatively spliced transcript variants of this gene have been described, however, the full-length nature of many ofthem is not known.

forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable