SAB2700185
Anti-Gli1 antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Sinônimo(s):
AV235269, Gli1, Zfp-5, Zfp5
Faça loginpara ver os preços organizacionais e de contrato
About This Item
Código UNSPSC:
12352203
NACRES:
NA.41
Produtos recomendados
fonte biológica
rabbit
Nível de qualidade
conjugado
unconjugated
forma do anticorpo
affinity isolated antibody
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
forma
buffered aqueous solution
reatividade de espécies
human
técnica(s)
western blot: 1:500-1:3000
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
wet ice
temperatura de armazenamento
−20°C
modificação pós-traducional do alvo
unmodified
Informações sobre genes
mouse ... Gli1(14632)
Descrição geral
GLI-Kruppel family member Gli1 is a transcriptional activator, which is part of the Gli family of transcription factors. It is a target of hedgehog signaling.
Imunogênio
Synthetic peptide containing a sequence corresponding to a region within amino acids 755 and 810 of Gli1 according to NP_034426
Aplicação
Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Ações bioquímicas/fisiológicas
GLI-Kruppel family member Gli1 may regulate the transcription of specific genes during normal development. It may also play a role in osteoblast formation, craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. The protein mediates SHH signaling and thus cell proliferation and differentiation. Gli1 may also be involved in tissue repair in pancreas. This protein has a protective role during stroke, ischemic injury and Parkinson′s disease.
Características e benefícios
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
forma física
1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Não está encontrando o produto certo?
Experimente o nosso Ferramenta de seleção de produtos.
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Aquatic Chronic 3 - Skin Sens. 1
Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
Gli1 haploinsufficiency leads to decreased bone mass with an uncoupling of bone metabolism in adult mice.
Kitaura Y
PLoS ONE (2014)
The transcription factor GLI1 modulates the inflammatory response during pancreatic tissue remodeling.
Mathew E
The Journal of Biological Chemistry (2014)
Gli1 activation and protection against hepatic encephalopathy is suppressed by circulating transforming growth factor ?1 in mice.
McMillin M
Journal of Hepatology (2014)
Fengjiao Liu et al.
CNS neuroscience & therapeutics, 27(12), 1518-1530 (2021-09-05)
Medulloblastoma (MB) is a malignant pediatric brain tumor that arises in the cerebellar granular neurons. Sonic Hedgehog subtype of MB (SHH-MB) is one of the major subtypes of MB in the clinic. However, the molecular mechanisms underlying MB tumorigenesis are
Young-Eun Leem et al.
PloS one, 9(11), e111701-e111701 (2014-11-05)
Hedgehog (Hh) signaling plays essential roles in various developmental processes, and its aberrant regulation results in genetic disorders or malignancies in various tissues. Hyperactivation of Hh signaling is associated with lung cancer development, and there have been extensive efforts to
Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.
Entre em contato com a assistência técnica