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Documentos Principais

SAB1301555

Sigma-Aldrich

ANTI-CD163 (N-TERM) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Sinônimo(s):

CD163, CD_antigen=CD163, Hemoglobin scavenger receptor, M130, Scavenger receptor cysteine-rich type 1 protein M130, Soluble CD163, sCD163

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

100

conjugado

unconjugated

forma do anticorpo

IgG fraction of antiserum

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

Formulário

buffered aqueous solution

peso molecular

125437 Da

reatividade de espécies

human

técnica(s)

immunohistochemistry: 1:50-1:100
western blot: 1:250-1:500

nº de adesão UniProt

Q86VB7

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... CD163(9332)

forma física

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

nwg

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
SH090630BB

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Morten N Andersen et al.
European journal of haematology, 93(1), 41-47 (2014-03-13)
Macrophages play an important role in cancer by suppression of adaptive immunity and promotion of angiogenesis and metastasis. Tumor-associated macrophages strongly express the hemoglobin scavenger receptor CD163, which can also be found as a soluble protein in serum and other
Francesca Bellora et al.
European journal of immunology, 44(6), 1814-1822 (2014-02-11)
We analyzed the functional outcome of the interaction between tumor-associated macrophages (TAMs) and natural killer (NK) cells. TAMs from ascites of ovarian cancer patients displayed an alternatively activated functional phenotype (M2) characterized by a remarkably high frequency and surface density
Nobuhiro Fujita et al.
Oncology reports, 31(6), 2499-2505 (2014-04-17)
The role of tumor-associated macrophages (TAMs) in hepatocellular carcinoma (HCC) has not been fully investigated. The aim of the present study was to clarify whether TAMs are associated with the angiogenesis of HCC during its multistep development, especially at an
Vasanthi R Sunil et al.
Experimental and molecular pathology, 97(1), 89-98 (2014-06-03)
Nitrogen mustard (NM) is a toxic alkylating agent that causes damage to the respiratory tract. Evidence suggests that macrophages and inflammatory mediators including tumor necrosis factor (TNF)α contribute to pulmonary injury. Pentoxifylline is a TNFα inhibitor known to suppress inflammation.
Tsung-Han Wu et al.
Cellular immunology, 290(1), 107-115 (2014-06-25)
We developed an in vitro model to evaluate the effect of products secreted from different colorectal cancer (CRC) cell lines on specific phenotypic switching and functional alterations in THP-1 cells. We co-cultured the human monocytic cell line, THP-1, or phorbol-12-myristate-13-acetate

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