RAB0016
Human Angiopoietin-2 ELISA Kit
for serum, plasma, cell culture supernatant and urine
Sinônimo(s):
Angiopoietin-2
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About This Item
Código UNSPSC:
41116158
NACRES:
NA.32
Produtos recomendados
reatividade de espécies
human
embalagem
kit of 96 wells (12 strips x 8 wells)
técnica(s)
ELISA: suitable
capture ELISA: suitable
entrada
sample type urine
sample type serum
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 10 pg/mL
standard curve range: 4.12-3000 pg/mL
método de detecção
colorimetric
Condições de expedição
wet ice
temperatura de armazenamento
−20°C
Informações sobre genes
human ... ANGPT2(285)
Descrição geral
The Human Angiopoietin-2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Angiopoietin-2 in serum, plasma, cell culture supernatants and urine.
Imunogênio
Recombinant Human Angiopoietin-2
Aplicação
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Ações bioquímicas/fisiológicas
Angiopoietin-2 (ANGPT2) belongs to the family of angiogenic factors. ANGPT2 is a competitive antagonist of ANGPT1 and reduces vascular stabilization. ANGPT2 is a potent marker for liver cancer. ANGPT2 binds with tyrosine kinase with immunoglobulin-like and endothelial growth factor (EGF)-like domains 2 (Tie-2) and causes neoangiogenesis in liver cirrhosis. Upregulation of ANGPT2 might have an adverse effect on kidney physiology and function. Overexpression of ANGPT2 leads to endothelial damage and dysfunction resulting in diabetic nephropathy in diabetic patients. ANGPT2 is a potent marker for detecting lung cancer progression. Upregulation of ANGPT2 promotes signal transduction for tumor progression in epithelial ovarian cancer.
Outras notas
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Met. Corr. 1
Código de classe de armazenamento
8A - Combustible corrosive hazardous materials
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Angiopoietin-2 serum levels are elevated in patients with liver cirrhosis and hepatocellular carcinoma
Scholz A, et al.
The American Journal of Gastroenterology, 102(11), 2471-2481 (2007)
Crosstalk between TEMs and endothelial cells modulates angiogenesis and metastasis via IGF1-IGF1R signalling in epithelial ovarian cancer
Wang X, et al.
British Journal of Cancer, 117(9), 1371-1382 (2017)
Angiopoietin-2, Renal Deterioration, Major Adverse Cardiovascular Events and All-Cause Mortality in Patients with Diabetic Nephropathy
Tsai YC, et al.
Kidney & Blood Pressure Research, 43, 545-554 (2018)
The role of serum angiopoietin-2 levels in progression and prognosis of lung cancer: A meta-analysis
Xu Y, et al.
Medicine, 96(37), e8063-e8063 (2017)
Angiopoietin-2 (Ang-2) is a useful serum tumor marker for liver cancer in the Chinese population
Chen Y, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 478, 18-27 (2018)
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