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Key Documents

PRS4379

Sigma-Aldrich

Anti-Nhe-1 (ab2) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Sinônimo(s):

Anti-Na+/H+ antiporter, Anti-SLC9A1, Anti-Sodium-hydrogen exchanger 1, Anti-Solute carrier family 9 (sodium/hydrogen exchanger), member 1, Anti-Solute carrier family 9 member 1

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.43

fonte biológica

rabbit

Nível de qualidade

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

forma

buffered aqueous solution

reatividade de espécies

mouse, human, rat

técnica(s)

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

nº de adesão UniProt

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... SLC9A1(6548)

Categorias relacionadas

Descrição geral

SLC9A1 (solute carrier family 9 member A1)/Na+/H+ exchanger 1 (NHE1), a plasma membrane transporter, is mapped to human chromosome 1p36. It belongs to the NHE family. NHE1 is abundantly expressed in all organisms.

Imunogênio

a 17 amino acid peptide near the center of the human Nhe-1.

Aplicação

Anti-Nhe-1 (ab2) antibody has been used in immunohistochemistry.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Ações bioquímicas/fisiológicas

Na+/H+ exchanger 1 (NHE1) modulates intracellular pH by exchanging a proton for an extracellular sodium ion and affects cell growth, proliferation, migration and apoptosis. It plays a major role in cancers including breast cancer, hepatocellular carcinoma, colon cancer, pancreatic ductal adenocarcinoma, prostate cancer, cervical cancer and neuroblastoma.

Ligação

The action of this antibody can be blocked using blocking peptide SBP4379.

forma física

Solution in phosphate buffered saline containing 0.02% sodium azide

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Effects and mechanism of Xin Mai Jia in a rabbit model of atherosclerosis.
Zhao FR, et al.
Experimental and Therapeutic Medicine, 10(5), 1627-1634 (2015)
Na+/H+ exchanger 1 has tumor suppressive activity and prognostic value in esophageal squamous cell carcinoma.
Ariyoshi Y, et al.
Oncotarget, 8(2), 2209-2209 (2017)
D S Lim et al.
Journal of the American College of Cardiology, 38(4), 1175-1180 (2001-10-05)
The goal of this study was to identify genes upregulated in the heart in human patients with hypertrophic cardiomyopathy (HCM). Hypertrophic cardiomyopathy is a genetic disease caused by mutations in contractile sarcomeric proteins. The molecular basis of diverse clinical and
Fan-Rong Zhao et al.
Experimental and therapeutic medicine, 10(5), 1627-1634 (2015-12-08)
The aim of this study was to investigate the protective effects of Xin Mai Jia (XMJ) on atherosclerosis (AS) in rabbits and to explore the underlying mechanisms in order to provide experimental evidence for the clinical application of XMJ. An

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