P4623

Anti-phospho-Interferon-α Receptor Type I (pSer⁵³⁵/pSer⁵³⁹) Subunit 1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinônimo(s): Anti-phospho-IFNα Receptor Type I (pSer⁵³⁵/pSer⁵³⁹) Subunit 1, Anti-phospho-IFNARI
• Número MDL: MFCD07370443
• Código UNSPSC: 12352203
• NACRES: NA.46

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• reatividade de espécies: rat, mouse, bovine, human
• técnica(s): western blot: 1:1,000 using using FLAG^® immunoprecipitates from HEK 293 cells transfected with Mock, IFNAR1 wild type, or IFNAR1 S535A and S539A mutants
• nº de adesão UniProt: P17181
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pSer535/pSer539)
• Informações sobre genes: human ... IFNAR1(3454) ; mouse ... Ifnar1(15975) ; rat ... Ifnar1(288264)

Descrição

Imunogênio

synthetic phosphopeptide corresponding to the amino acid residues surrounding the human phospho-interferon-α receptor type I (pSer⁵³⁵/pSer⁵³⁹) subunit 1.

Ações bioquímicas/fisiológicas

Type I interferons (IFNα, IFNβ and IFNω) are pleotropic cytokines that mediate their cellular activities by binding to specific Type I IFN receptors. The functions of IFNα/ IFNα Receptor Type I axis include antiproliferative, antiviral and immunomodulatory activities.

forma física

Solution in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA, and 50% glycerol.

Informações legais

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)