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I9764

Sigma-Aldrich

Anti-Human IgG (γ-chain specific) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

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About This Item

Número MDL:
MFCD00162442
Código UNSPSC:
12352203
NACRES:
NA.46

fonte biológica

rabbit

Nível de qualidade

300

conjugado

unconjugated

forma do anticorpo

IgG fraction of antiserum

tipo de produto de anticorpo

secondary antibodies

clone

polyclonal

forma

buffered aqueous solution

técnica(s)

immunoelectrophoresis: suitable
indirect ELISA: 1:50,000
quantitative precipitin assay: 2.0-3.0 mg/mL

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Categorias relacionadas

Descrição geral

IgG (immunoglobulin G) antibody subtype is a predominant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. IgG is found in four subclasses IgG1, IgG2, IgG3 and IgG4. IgG has a monomeric structure.

Aplicação

Anti-Human IgG (γ-chain specific) antibody produced in rabbit has been used in western blotting.
Anti-Human IgG (γ-chain specific) antibody produced in rabbit was conjugated with BSA and coated over a nanofibrillar cellulose film to develop a platform for immunoassays and diagnostics.

Ações bioquímicas/fisiológicas

IgG (immunoglobulin G) antibody participates in complement fixation and opsonization.
IgG antibody subtype provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

nwg

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Protein disulfide isomerase does not control recombinant IgG4 productivity in mammalian cell lines
Hayes NVL, et al.
Biotechnology and Bioengineering, 105(4), 770-779 (2010)
Comparison of antibody molecules produced from two cell lines with contrasting productivities and aggregate contents
Ishii Y, et al.
Biological & Pharmaceutical Bulletin, b14-00729 (2014)
Hannes Orelma et al.
Biointerphases, 7(1-4), 61-61 (2012-10-12)
We introduce a new method to modify films of nanofibrillated cellulose (NFC) to produce non-porous, water-resistant substrates for diagnostics. First, water resistant NFC films were prepared from mechanically disintegrated NFC hydrogel, and then their surfaces were carboxylated via TEMPO-mediated oxidation.
IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4
Avery DT, et al.
Journal of Immunology, 181(3), 1767-1779 (2008)
Placental transfer of IgG subclasses in a Japanese population.
Hashira S, et al.
Pediatrics International, 42(4) (2000)
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Artigos

Anti-Human Antibodies for COVID-19 (SARS-CoV-2) Immunoglobulin Detection Research

Antibody-based serology tests are useful in identifying subjects with an adaptive immune response to the SARS-CoV-2 virus. Anti-human immunoglobulin antibodies allow for quick and simple, yet reliable assays with easy readouts and can also be adapted for high-throughput screening.

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