I2273

3-Indoleacrylic acid

≥98% (HPLC), BioReagent

• Sinônimo(s): 3-(3-Indolyl)acrylic acid, IAA
• Fórmula empírica (Notação de Hill): C₁₁H₉NO₂
• Número CAS: 1204-06-4
• Peso molecular: 187.19
• Beilstein: 6317
• Número CE: 214-872-7
• Número MDL: MFCD00005633
• Código UNSPSC: 12352106
• ID de substância PubChem: 24895972
• NACRES: NA.52

Propriedades

• grau: for molecular biology
• linha de produto: BioReagent
• Ensaio: ≥98% (HPLC)
• Formulário: powder
• peso molecular: 187.19 g/mol
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: OC(=O)\C=C\c1c[nH]c2ccccc12
• InChI: 1S/C11H9NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-7,12H,(H,13,14)/b6-5+
• chave InChI: PLVPPLCLBIEYEA-AATRIKPKSA-N

Descrição

Descrição geral

3-Indoleacrylic acid (IAA) is a chemical used for the induction of gene transcription. This expression system requires that the gene of interest is cloned in plasmids containing the trpE promoter.

Aplicação

3-Indoleacrylic acid has been used in the induction of ribokinase expression in E. coli.

Ações bioquímicas/fisiológicas

3-Indoleacrylic acid (IAA) is metabolized from tryptophan and this conversion is carried out by gut microflora. 3-Indoleacrylic acid (IAA) is a chemical used for the induction of gene transcription. The IAA induced expression system requires the gene of interest cloned in plasmids containing the trp promoter. It promotes the barrier functionality of the intestinal epithelial cells. IAA also favors anti-inflammatory response and is regarded as a potential therapeutic to treat inflammatory bowel disease (IBD). It is also implicated in a variety of cellular processes including apoptosis, autophagy, cell proliferation and migration. In tumor cells, IAA is also reported to hinder tryptophan metabolism.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315,H319,H335
• Declarações de precaução: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves