GE17-5481-51

HiTrap^® Capto^™ Core 700

Cytiva 17-5481-51, pack of 5 × 1 mL

• Sinônimo(s): Capto Core 700 Column
• Código UNSPSC: 23151817
• NACRES: NA.56

Propriedades

• ligand: octylamine
• embalagem: pack of 5 × 1 mL
• fabricante/nome comercial: Cytiva 17-5481-51
• Parâmetros: 5 bar
• D.I. da coluna: 7 mm
• Matriz: highly cross-linked agarose
• Tamanho médio da partícula: 75 (d₅₀v is the median particle size of the cumulative volume distribution)
• cleaning: 3-14(pH interval where the medium can be subjected to, for cleaning- or sanitization-in-place.)
• Faixa de trabalho: 2-14(pH interval where the medium can be operated without significant change in function.)
• capacidade: ~13 mg binding capacity (ovalbumin)
• adequação: suitable for bioprocess medium

Descrição

Descrição geral

Dynamic binding capacities were measured at 10% breakthrough with a residence time of 3 min (1.6 ml/min = 200 cm/h) in HiScreen columns. Buffer: 20 mM Tris-HCl, 150 mM NaCl, pH 7.5.

HiTrap Capto Core 700 is prepacked with Capto Core 700, a multimodal BioProcess resin for intermediate purification and polishing of viruses and other large biomolecules. Capto Core 700 is a novel, layered bead chromatography resin consisting of a porous outer layer and ligand-activated core. The octylamine ligands found in the core of the beads are multimodal, being both hydrophobic and positively charged. These internalized ligands bind impurities strongly over a wide range of pH and salt concentration. The pores of the bead outer layer prevent large targets (Mr > 700 000) from binding to the ligands while smaller impurities can enter freely into the beads where they are captured.

Características e benefícios

• High capacity and productivity in flowthrough mode.
• Prepacked HiTrap columns for easy screening and convenient process development, as well as small scale purification.
• Wide operational window of pH and conductivity.

Armazenamento e estabilidade

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

Store at 4 to 30 °C (20% Ethanol)

Nota de análise

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Informações legais

Capto is a trademark of Cytiva

HiTrap is a registered trademark of Cytiva

Informações de segurança

• Pictogramas: GHS02
• Palavra indicadora: Warning
• Frases de perigo: H226
• Declarações de precaução: P280 - P210 - P241 - P235 - P303 + P361 + P353 - P501
• Código de classe de armazenamento: 3 - Flammable liquids