GE17-1279-02
rProtein A Sepharose™ Fast Flow
Cytiva 17-1279-02, pack of 25 mL
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About This Item
Código UNSPSC:
41106500
NACRES:
NA.56
Produtos recomendados
ligand
recombinant protein A (E. coli)
embalagem
pack of 25 mL
fabricante/nome comercial
Cytiva 17-1279-02
condição de armazenamento
(20% Ehtanol)
matriz
4% cross-linked agarose
tamanho de partícula
60-165 μm
diâmetro médio
90 μm (d50v)
cleaning in place
2-11
working range
3-10
capacidade
~50 mg binding capacity (human lgG/ml medium)
adequação
suitable for bioprocess medium
temperatura de armazenamento
2-8°C
Categorias relacionadas
Descrição geral
rProtein A Sepharose 4 Fast Flow is an affinity resin for antibody purification at laboratory and process scale.
Monoclonal and polyclonal antibody purification
rProtein A Sepharose 4 Fast Flow is built upon the well-established Sepharose Fast Flow platform and is used in many approved monoclonal antibody processes. It is composed of recombinant protein A coupled to the cross-linked 4% agarose base matrix.The highly crosslinked agarose resin enables high flow rates and high productivity.
Protein A resin characteristics
The recombinant protein is produced in E. coli and engineered with an oriented coupling to enhance binding capacity. Epoxy-based coupling ensures low ligand leakage. Specificity of the recombinant protein for the Fc region of IgG is similar to the native protein, giving a high degree of selectivity and yield.
Streamlined scale up
Scale-up with this resin is straightforward and is further aided by a range of prepacked process development tools, making purification scale-up straightforward.
Monoclonal and polyclonal antibody purification
rProtein A Sepharose 4 Fast Flow is built upon the well-established Sepharose Fast Flow platform and is used in many approved monoclonal antibody processes. It is composed of recombinant protein A coupled to the cross-linked 4% agarose base matrix.The highly crosslinked agarose resin enables high flow rates and high productivity.
Protein A resin characteristics
The recombinant protein is produced in E. coli and engineered with an oriented coupling to enhance binding capacity. Epoxy-based coupling ensures low ligand leakage. Specificity of the recombinant protein for the Fc region of IgG is similar to the native protein, giving a high degree of selectivity and yield.
Streamlined scale up
Scale-up with this resin is straightforward and is further aided by a range of prepacked process development tools, making purification scale-up straightforward.
Características e benefícios
- For monoclonal and polyclonal antibody purification at both laboratory and process scale.
- Well established among Protein A resins as excellent for monoclonal antibody (mAb) processes.
- Free from animal-derived components.
- Hydrophilic base matrix ensures low levels of non-specific binding and low levels of host cell-derived impurities in the elution pool.
- Fulfills industrial demands for security of supply, robust performance, and regulatory support.
Armazenamento e estabilidade
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Nota de análise
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
Informações legais
Sepharose is a trademark of Cytiva
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Código de classe de armazenamento
3 - Flammable liquids
Certificados de análise (COA)
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