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C8912

Sigma-Aldrich

Cocaine free base

Sinônimo(s):

Ecgonine methyl ester benzoate

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About This Item

Fórmula empírica (Notação de Hill):
C17H21NO4
Número CAS:
50-36-2
Peso molecular:
303.35
Número CE:
200-032-7
Número MDL:
MFCD00056906
Código UNSPSC:
12352200
ID de substância PubChem:
24893116
NACRES:
NA.77

forma

powder

controle de medicamentos

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal)

aplicação(ões)

forensics and toxicology

cadeia de caracteres SMILES

[H][C@]12CC[C@]([H])([C@H]([C@H](C1)OC(=O)c3ccccc3)C(=O)OC)N2C

InChI

1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1

chave InChI

ZPUCINDJVBIVPJ-LJISPDSOSA-N

Informações sobre genes

human ... DRD3(1814) , KCNH1(3756) , KCNH2(3757) , SCN10A(6336) , SCN11A(11280) , SCN5A(6331) , SLC6A2(6530) , SLC6A3(6531) , SLC6A4(6532)
mouse ... Slc6a2(20538)
rat ... Chrm1(25229) , Slc6a3(24898) , Slc6a4(25553)

Ações bioquímicas/fisiológicas

Inhibits the dopamine, norepinephrine, and serotonin transporters with Kis of about 300 nM, 900 nM, and 400 nM, respectively. Unlike amphetamines, it has no effect on catecholamine release.

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palavra indicadora

Danger

Frases de perigo

H300 + H330,H336,H361d

Classificações de perigo

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Repr. 2 - STOT SE 3

Órgãos-alvo

Central nervous system

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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