A5963

Anti-c-Myc−Alkaline Phosphatase antibody, Mouse monoclonal

clone 9E10, purified from hybridoma cell culture

• Sinônimo(s): Anti-c-Myc, Monoclonal Anti-c-Myc−Alkaline Phosphatase antibody produced in mouse
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 200
• conjugado: alkaline phosphatase conjugate
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: 9E10, monoclonal
• Formulário: buffered aqueous glycerol solution
• reatividade de espécies: human
• técnica(s): ELISA: suitable; immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; western blot: 1:100 using a myc-tagged fusion protein.
• Isotipo: IgG1
• nº de adesão UniProt: P01106
• temperatura de armazenamento: 2-8°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... MYC(4609)

Descrição

Descrição geral

Monoclonal Anti-c-myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized BALB/c mouse. The c-myc gene encodes for a protein of 62kDa called p62^c-myc is associated mainly with cell nuclei.

Imunogênio

synthetic peptide of the human p62^c-Myc protein.

Aplicação

Anti-c-Myc-Alkaline Phosphatase antibody has been used in

• enzyme linked immunosorbent assay (ELISA)
• immunohistochemical labeling
• immunostaining
• western blotting

Monoclonal Anti-c-Myc-Alkaline Phosphatase antibody can be used for western blot assays at 1:100, using myc-tagged fusion proteins. The antibody can also be used for immunohistochemical applications.

Ações bioquímicas/fisiológicas

The c-myc oncogene product(p62^c-myc) exerts normal and oncogenic cellular functions. Elevated level of c-myc protein in malignant tissues when compared with normal tissue, but with the unexpected finding of a cytoplasmic accumulation of the protein in these tumors.

forma física

Solution in 0.05 M Tris buffer, containing 1% bovine serum albumin, 1 mM MgCl₂, 50% glycerol, and 15 mM sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)