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Documentos Principais

306M-2

Sigma-Aldrich

NSE (MRQ-55) Mouse Monoclonal Antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

mouse

Nível de qualidade

100
500

conjugado

unconjugated

forma do anticorpo

culture supernatant

tipo de produto de anticorpo

primary antibodies

clone

MRQ-55, monoclonal

descrição

For In Vitro Diagnostic Use in Select Regions (See Chart)

Formulário

buffered aqueous solution

reatividade de espécies

human

embalagem

vial of 0.1 mL concentrate (306M-24)
vial of 0.5 mL concentrate (306M-25)
bottle of 1.0 mL predilute (306M-27)
vial of 1.0 mL concentrate (306M-26)
bottle of 7.0 mL predilute (306M-28)

fabricante/nome comercial

Cell Marque®

técnica(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

Isotipo

IgG2b

controle

appendix/colon, schwannoma

Condições de expedição

wet ice

temperatura de armazenamento

2-8°C

visualização

cytoplasmic

Informações sobre genes

human ... ENO2(2026)

Descrição geral

Neuron-specific enolase (NSE) is a glycolytic isoenzyme of the enolase gamma-gamma dimerselectively detected in neurons, peripheral nerves, some neuroendocrine cells, and tumors.NSE immunoreactivity is also observed, to a lesser extent, in smooth muscle tissue. Anti-NSEis often used to visualize peripheral nerves and for the identification of neuroendocrinedifferentiation.

Qualidade


IVD

IVD

IVD

RUO

Ligação

NSE Positive Control Slides, Product No. 306S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

forma física

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota de preparo

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Outras notas

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informações legais

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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N Leonard et al.
Gut, 37(6), 763-765 (1995-12-01)
The pathogenesis of villous damage in coeliac disease is unknown. Change to the delicate neuromuscular core may be significant and this study stained various categories of coeliac disease and controls with neuron-specific enolase (NSE) to examine neurofilaments in the mucosa.
M R Wick et al.
American journal of clinical pathology, 79(6), 703-707 (1983-06-01)
In order to better define the use of neuron-specific enolase (NSE) as a marker for neuroendocrine neoplasms, we studied 11 thymic carcinoid tumors, three bronchial small-cell carcinomas (all with cutaneous metastases), and 10 trabecular carcinomas of the skin for its
A S Leong et al.
Pathology, 18(4), 393-399 (1986-10-01)
Thirteen cases of primary endocrine carcinoma of the skin (Merkel cell carcinoma) were reviewed with the aim of defining the morphological, immunohistochemical and ultrastructural criteria for diagnosis. The tumour cells were characterized by their scanty cytoplasm, generally small uniform nuclei
E H Cooper
The International journal of biological markers, 9(4), 205-210 (1994-10-01)
The clinical value of neuron-specific enolase as a marker is small cell lung cancer, neuroblastoma, melanoma and seminoma has been reviewed. The role of serum and cerebrospinal NSE in benign and malignant disease of the central nervous system is discussed.
S A Vinores et al.
Archives of pathology & laboratory medicine, 108(7), 536-540 (1984-07-01)
In normal conditions, neuron-specific enolase (NSE) is histochemically demonstrable only in neurons and cells of the amine precursor uptake and decarboxylation (APUD) system. This has been found not to be true for neoplastic cells. Several types of CNS tumors, including

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