27555

Cloxacillin sodium salt

≥95.0% (HPLC)

• Sinônimo(s): 3-(o-Chlorophenyl)-5-methyl-4-isoxazolylpenicillin sodium salt, Syntarpen sodium salt
• Fórmula empírica (Notação de Hill): C₁₉H₁₇ClN₃NaO₅S
• Número CAS: 642-78-4
• Peso molecular: 457.86
• Beilstein: 4103180
• Número CE: 211-390-9
• Número MDL: MFCD00063568
• Código UNSPSC: 51102829
• ID de substância PubChem: 57648259
• NACRES: NA.85

Propriedades

• fonte biológica: semisynthetic
• Nível de qualidade: 200
• Ensaio: ≥95.0% (HPLC)
• Formulário: powder or crystals
• Impurezas: ≤5% Total impurities (anhydrous)
• cor: white to off-white
• espectro de atividade do antibiótico: Gram-positive bacteria
• Modo de ação: cell wall synthesis | interferes
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: [Na+].Cc1onc(-c2ccccc2Cl)c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C([O-])=O
• InChI: 1S/C19H18ClN3O5S.Na/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23;/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27);/q;+1/p-1/t13-,14+,17-;/m1./s1
• chave InChI: SCLZRKVZRBKZCR-SLINCCQESA-M

Descrição

Descrição geral

Chemical structure: ß-lactam

Aplicação

Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is used against staphylococci that produce β-lactamase. It is used to study the role of pH in antibiotic effectiveness and how oxgall, acid, and hydrogen peroxide stress effects the susceptibility of Bifidobacteria.

Ações bioquímicas/fisiológicas

Cloxacillin interferes with the last stage of bacterial cell wall synthesis by binding to penicillin-binding proteins. This inhibits the necessary cross-linking and leads to autolysis of the bacteria by autolysins.

Outras notas

Keep container tightly closed in a dry and well-ventilated place.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)