Y0001426

Carvedilol for system suitability

European Pharmacopoeia (EP) Reference Standard

• Sinônimo(s): Carvedilol, 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol, BM-14190
• Fórmula empírica (Notação de Hill): C₂₄H₂₆N₂O₄
• Número CAS: 72956-09-3
• Peso molecular: 406.47
• Número MDL: MFCD00864692
• Código UNSPSC: 41116107
• ID de substância PubChem: 329831421
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: carvedilol
• fabricante/nome comercial: EDQM
• aplicação(ões): pharmaceutical (small molecule)
• formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: OC(COC1=CC=CC2=C1C3=C(C=CC=C3)N2)CNCCOC4=CC=CC=C4OC
• InChI: 1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3
• chave InChI: OGHNVEJMJSYVRP-UHFFFAOYSA-N
• Informações sobre genes: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRB1(153) , ADRB2(154) , ADRB3(155)

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Carvedilol for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Ações bioquímicas/fisiológicas

Cavedilol is a non-selective β-adrenergic blocker with α1 blocking activity. Carvedilol is used specifically for the treatment of heart failure and high blood pressure. It has been shown to improve left ventricular ejection fraction and may reduce mortality.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS08,GHS09
• Palavra indicadora: Warning
• Frases de perigo: H373,H411
• Declarações de precaução: P260 - P273 - P314 - P391 - P501
• Classificações de perigo: Aquatic Chronic 2 - STOT RE 2
• Órgãos-alvo: Liver,spleen,Uterus (including cervix),Adrenal gland
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable