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Y0001333

Clopidogrel hydrogen sulfate

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

(S)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogensulfate

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About This Item

Fórmula empírica (Notação de Hill):
C16H16ClNO2S · H2SO4
Número CAS:
120202-66-6
Peso molecular:
419.90
Beilstein:
9967887
Número MDL:
MFCD00876395
Código UNSPSC:
41116107
ID de substância PubChem:
329831368
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

clopidogrel

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

OS(O)(=O)=O.COC(=O)[C@@H](N1CCc2sccc2C1)c3ccccc3Cl

InChI

1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)/t15-;/m0./s1

chave InChI

FDEODCTUSIWGLK-RSAXXLAASA-N

Informações sobre genes

human ... P2RY12(64805)

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Clopidogrel hydrogen sulfate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

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Clopidogrel for system suitability, European Pharmacopoeia (EP) Reference Standard

Y0001335

Clopidogrel impurity A, European Pharmacopoeia (EP) Reference Standard

PHR1992

Clopidogrel Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1991

Clopidogrel Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1990

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Pictogramas

CorrosionEnvironment
GHS05,GHS09

Palavra indicadora

Danger

Frases de perigo

H314,H411

Classificações de perigo

Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B

Código de classe de armazenamento

8A - Combustible corrosive hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number

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Kyoung-Woo Seo et al.
Clinical therapeutics, 36(11), 1588-1594 (2014-09-15)
Platelet-function suppression with antiplatelet therapy is effective in preventing and treating cardiovascular disease. Clopidogrel is a thienopyridine derivative that blocks platelet activation by adenosine diphosphate receptor binding. This study demonstrates the effects of generic clopidogrel bisulfate in comparison to branded
Xinmeng Chen et al.
Biopharmaceutics & drug disposition, 36(1), 64-68 (2014-09-27)
Erigeron breviscapus (Vant.) Hand-Mazz, a traditional Chinese medicine, is often co-prescribed with clopidogrel for the treatment of ischemic vascular diseases. Scutellarin is the representative bioactive flavonoid isolated from this herb. The aim of this study was to explore the effect
Matteo Tozzi et al.
Journal of vascular surgery, 60(4), 1019-1023 (2014-05-14)
An alternative surgical technique for the repair an aneurysmatic arteriovenous fistula (AVF) using a staple remodeling operation has been developed and the results are reported. All patients presenting with an aneurysmatic autogenous AVF of the upper extremities between January 2012
Lucia Stefanini et al.
The Journal of clinical investigation, 125(4), 1419-1432 (2015-02-24)
The small GTPase RAP1 is critical for platelet activation and thrombus formation. RAP1 activity in platelets is controlled by the GEF CalDAG-GEFI and an unknown regulator that operates downstream of the adenosine diphosphate (ADP) receptor, P2Y12, a target of antithrombotic
Wei Li et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 88(3), 706-717 (2014-10-14)
Chemical modification of nanoclay will ensure further progress on these materials. In this work, we show that montmorillonite (MTM) nanosheets can be modified with β-cyclodextrin (CD) via a nucleophilic substitution reaction between mono-6-(p-toluenesulfonyl)-6-deoxy-β-CD and an amino group of 3-aminopropyltriethoxysilane (APTES)-functionalized

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