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Y0001238

Sulfinpyrazone for system suitability

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

(±)-Sulfinpyrazone, 1,2-Diphenyl-4-(phenylsulfinylethyl)-3,5-pyrazolidinedione, Diphenylpyrazone

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About This Item

Fórmula empírica (Notação de Hill):
C23H20N2O3S
Número CAS:
57-96-5
Peso molecular:
404.48
Número MDL:
MFCD00057279
Código UNSPSC:
41116107
ID de substância PubChem:
329831317
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

sulfinpyrazone

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

O=C1C(CCS(=O)c2ccccc2)C(=O)N(N1c3ccccc3)c4ccccc4

InChI

1S/C23H20N2O3S/c26-22-21(16-17-29(28)20-14-8-3-9-15-20)23(27)25(19-12-6-2-7-13-19)24(22)18-10-4-1-5-11-18/h1-15,21H,16-17H2

chave InChI

MBGGBVCUIVRRBF-UHFFFAOYSA-N

Informações sobre genes

human ... SLC22A12(116085)

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Sulfinpyrazone for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

produto relacionado

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Preços

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302

Declarações de precaução

P301 + P312 + P330

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Lot/Batch Number

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E H Margulies et al.
Drugs, 20(3), 179-197 (1980-09-01)
Sulfinpyrazone1 has long been recognised as a potent uricosuric agent, but has more recently been studied extensively as a platelet inhibitor and antithrombotic agent. It is active in man following oral administration and has been reported to be effective in
Sulfinpyrazone: relationship between dose, kinetics, plasma concentrations and biological effects.
M R Buchanan
Thrombosis research. Supplement, 4, 89-92 (1983-01-01)
Ashley M Laughney et al.
Science translational medicine, 6(261), 261ra152-261ra152 (2014-11-08)
Eribulin mesylate was developed as a potent microtubule-targeting cytotoxic agent to treat taxane-resistant cancers, but recent clinical trials have shown that it eventually fails in many patient subpopulations for unclear reasons. To investigate its resistance mechanisms, we developed a fluorescent
Uricosuric drugs, with special reference to probenecid and sulfinpyrazone.
A B Gutman
Advances in pharmacology, 4, 91-142 (1966-01-01)
Andrew C Kotze et al.
Antimicrobial agents and chemotherapy, 58(12), 7475-7483 (2014-10-08)
We used an enzyme induction approach to study the role of detoxification enzymes in the interaction of the anthelmintic compound naphthalophos with Haemonchus contortus larvae. Larvae were treated with the barbiturate phenobarbital, which is known to induce the activity of
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