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RDD028

Sigma-Aldrich

Ethanolamine hydrochloride

anhydrous, free-flowing, Redi-Dri, ≥99.0%

Sinônimo(s):

Colamine hydrochloride, Ethanolamine chloride, 2-Aminoethanol hydrochloride

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About This Item

Fórmula linear:
H2NCH2CH2OH · HCl
Número CAS:
Peso molecular:
97.54
Beilstein:
3542892
Número MDL:
Código UNSPSC:
12352116

grau

anhydrous

Nível de qualidade

linha de produto

Redi-Dri

Ensaio

≥99.0%

qualidade

free-flowing

pKa (25 °C)

9.5

pf

82-84 °C (lit.)

cadeia de caracteres SMILES

NCCO.[H]Cl

InChI

1S/C2H7NO.ClH/c3-1-2-4;/h4H,1-3H2;1H

chave InChI

PMUNIMVZCACZBB-UHFFFAOYSA-N

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Descrição geral

Ethanolamine hydrochloride, a versatile compound in biochemistry and molecular biology, plays a pivotal role in diverse research areas. Primarily, it functions as a buffering agent, ensuring a stable pH environment crucial for enzymatic reactions, protein solubilization, and other biological processes. Its significance extends to membrane protein studies, aiding in the extraction of these proteins from cell membranes. It also finds utility in cell culture and as a reagent for biological sample preparation, simplifying nucleic acid and protein isolation, as well as facilitating the detection of proteins by western blotting and immunohistochemistry. This compound′s wide-ranging applications make it indispensable in biochemical research, contributing to various experimental procedures and advancing our understanding in fields such as molecular biology, immunology, and cellular biology.

Aplicação

Redi-Dri is an innovative packaging product line that helps eliminate clumping material by adding extra packaging process steps without any chemical additives, anti-clumping agents, or hydrophobic compounds. Redi-Dri offers a more convenient and safer way to handle the products.
Ethanolamine hydrochloride has been used:
  • in overnight incubation of the tips to attach primary amine groups at the tip surface
  • in the preparation of DMEM (dulbecco′s modified eagle′s medium)/F-12 media to culture human epidermal growth factor receptor 2 (HER2) cells derived from MMTV-HER2 transgenic mouse mammary tumors
  • to administer the cultures to study its effect on the endogenous phosphatidyl ethanolamine pool and autophagy process

Ações bioquímicas/fisiológicas

Ethanolamine hydrochloride is utilized as a carbon and nitrogen source by bacteria that differs phylogenetically. It exists as phosphotidylethanolamine in the bacterial and mammalian cell membrane. Ethanolamine-ammonia lyase is responsible for the degradation of ethanolamine into acetaldehyde and ammonia. Ethanolamine is known to positively support lipid accumulation in photosynthetic organism model.

Características e benefícios

  • Suitable for molecular biology
  • Redi-Dri packaging controls moisture for hygroscopic chemicals that commonly clump
  • Powder remains free-flowing and easy to use
  • Safer to handle and weigh out for routine use in the lab
  • Eliminates clumps, maintaining product moisture, quality, and product specifications

Outras notas

For additional information on our range of Biochemicals, please complete this form.

Informações legais

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Selective cyclin-dependent kinase 2/cyclin A antagonists that differ from ATP site inhibitors block tumor growth
Mendoza N, et al.
Cancer Research, 63(5), 1020-1024 (2003)
Amino Alcohols-Advances in Research and Application, 29-29 (2013)
Unbinding molecular recognition force maps of localized single receptor molecules by atomic force microscopy
Sotres J, et al.
ChemPhysChem, 9(4), 590-599 (2008)

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