PHR1319

Residual Solvent - Trichloroethylene

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinônimo(s): Trichloroethylene, TCE, Trichloroethene
• Fórmula linear: ClCH=CCl₂
• Número CAS: 79-01-6
• Peso molecular: 131.39
• Beilstein: 1736782
• Número MDL: MFCD00000838
• Código UNSPSC: 41116107
• ID de substância PubChem: 329823304

Propriedades

• grau: certified reference material; pharmaceutical secondary standard
• Nível de qualidade: 300
• Agency: traceable to USP 1601827
• densidade de vapor: 4.5 (vs air)
• pressão de vapor: 61 mmHg ( 20 °C)
• Certificado de análise (CofA): current certificate can be downloaded
• temperatura de autoignição: 770 °F
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• índice de refração: n20/D 1.476 (lit.)
• pb: 86.7 °C (lit.)
• pf: −84.8 °C (lit.)
• densidade: 1.463 g/mL at 25 °C (lit.)
• aplicação(ões): pharmaceutical (small molecule)
• formato: single component solution
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: Cl\C=C(\Cl)Cl
• InChI: 1S/C2HCl3/c3-1-2(4)5/h1H
• chave InChI: XSTXAVWGXDQKEL-UHFFFAOYSA-N

Descrição

Descrição geral

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Residual Solvent - Trichloroethylene belongs to the group of class 2 residual solvents. The use of class 2 solvents should be limited in drug substances, excipients, dietary ingredients, and official products because of the inherent toxicities of these residual solvents. Trichloroethylene is a volatile and chlorinated organic compound, which finds applications as a solvent and greasing agent.

Aplicação

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAA0678 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informações de segurança

• Pictogramas: GHS08
• Palavra indicadora: Danger
• Frases de perigo: H350
• Declarações de precaução: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classificações de perigo: Carc. 1B
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 188.6 °F - closed cup
• Ponto de fulgor (°C): 87 °C - closed cup