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Documentos Principais

PHR1181

Supelco

2-Methylimidazole (Ondansetron Impurity F)

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

2-Methylimidazole, Ondansetron impurity F, 2-Methylglyoxaline

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About This Item

Fórmula empírica (Notação de Hill):
C4H6N2
Número CAS:
Peso molecular:
82.10
Beilstein:
1368
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

Agency

traceable to Ph. Eur. Y0001320

pressão de vapor

<1 mmHg ( 0 °C)

família API

ondansetron

Certificado de análise (CofA)

current certificate can be downloaded

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

p.e.

267-268 °C (lit.)

pf

142-143 °C (lit.)

aplicação(ões)

pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-30°C

cadeia de caracteres SMILES

Cc1ncc[nH]1

InChI

1S/C4H6N2/c1-4-5-2-3-6-4/h2-3H,1H3,(H,5,6)

chave InChI

LXBGSDVWAMZHDD-UHFFFAOYSA-N

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Descrição geral

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAA9000 in the slot below. This is an example certificate only and may not be the lot that you receive.

produto relacionado

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Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Cristina Maccallini et al.
Bioorganic & medicinal chemistry letters, 20(22), 6495-6499 (2010-10-12)
A series of N-substituted acetamidines and 2-methylimidazole derivatives structurally related to W1400 were synthesized and evaluated as Nitric Oxide Synthase (NOS) inhibitors. Analogs with sterically hindering isopropyl and phenyl substituents on the benzylic carbon connecting the aromatic core of W1400
Jianfeng Li et al.
Inorganic chemistry, 49(5), 2398-2406 (2010-01-29)
The X-ray characterization of the five-coordinate picket-fence porphyrin complex, [Co(TpivPP)(2-MeHIm)], is reported. The complex has the displacement of cobalt from the porphyrin plane = 0.15 A, and Co-N(Im) = 2.145(3) and (Co-N(p))(av) = 1.979(3) A. This five-coordinate complex, in the
Kiriaki Pegklidou et al.
Journal of agricultural and food chemistry, 56(12), 4482-4490 (2008-05-23)
The potential role of 2-methyl imidazole in improving lycopene production by Blakeslea trispora with regards to yield, selectivity, and safety aspects was investigated in batch culture. Optimization of the bioprocess conditions in terms of (a) (+) and (-) strain ratio
Gianantonio Battistuzzi et al.
Journal of the American Chemical Society, 124(19), 5315-5324 (2002-05-09)
Axial iron ligation and protein encapsulation of the heme cofactor have been investigated as effectors of the reduction potential (E degrees ') of cytochrome c through direct electrochemistry experiments. Our approach was that of partitioning the E degrees ' changes
Akito Nakagawa et al.
Bioconjugate chemistry, 17(1), 146-151 (2006-01-19)
We have found that recombinant human serum albumin (HSA) incorporating tailed porphyrinatoiron(II) in the alpha,alpha,alpha,beta-conformer can reversibly bind and release O2 under physiological conditions (pH 7.3, 37 degrees C) like hemoglobin and myoglobin. beta-2-Methylimidazolyl-tailed porphyrinatoirons (6a, 6b) are synthesized via

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