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Documentos

B7536

Supelco

Buprenorphine hydrochloride solution

analytical standard, for drug analysis

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About This Item

Fórmula empírica (Notação de Hill):
C29H41NO4 · HCl
Número CAS:
Peso molecular:
504.10
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

analytical standard, for drug analysis

Nível de qualidade

drug control

Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

pharmaceutical (small molecule)

formato

single component solution

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

Cl.CO[C@]12CC[C@@]3(CC1[C@](C)(O)C(C)(C)C)[C@H]4Cc5ccc(O)c6OC2[C@]3(CCN4CC7CC7)c56

InChI

1S/C29H41NO4.ClH/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28;/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3;1H/t20-,21-,24-,26+,27-,28+,29-;/m1./s1

chave InChI

UAIXRPCCYXNJMQ-RZIPZOSSSA-N

Aplicação

Buprenorphine hydrochloride solution may be used as a reference standard in the determination of buprenorphine in samples of human plasma using gas chromatography coupled with mass spectrometry (GC/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órgãos-alvo

Eyes

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

51.8 °F - closed cup

Ponto de fulgor (°C)

11 °C - closed cup

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves


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Development and validation of a sensitive analytical method for the simultaneous determination of buprenorphine and norbuprenorphine in human plasma.
Gopal S, et al.
European Journal of Pharmaceutics and Biopharmaceutics, 51(2), 147-151 (2001)
Thomas Alexander et al.
Pediatrics, 131(3), e945-e949 (2013-02-20)
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare but increasingly described phenomenon of immune activation and organ dysfunction in association with a wide variety of medications. This reaction shows a broad spectrum of clinical presentation and
Afarin Rahimi-Movaghar et al.
The Cochrane database of systematic reviews, 1(1), CD007775-CD007775 (2013-02-27)
Pharmacologic therapies for maintenance treatment of heroin dependence have been used and studied widely. Systematic reviews have demonstrated the effectiveness of such therapies. Opium dependence is associated with less problems and impairments and is less likely to be used by
Huei-Ru Lin et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 925, 10-15 (2013-03-20)
For monitoring compliance of methadone or buprenorphine maintenance patient, a method for the simultaneous determination of methadone, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), buprenorphine, norbuprenorphine, opiates (morphine, codeine, 6-monoacetylmorphine) in urine by superficially porous liquid chromatography tandem mass spectrometry was developed and validated. After
E J Love et al.
The Veterinary record, 172(24), 635-635 (2013-06-06)
Buprenorphine has recently obtained UK Marketing Authorisation for horses. The analgesic effects are long lasting, and have considerable potential for postoperative pain relief. This observer blinded, randomised study aimed to evaluate postsurgical analgesia in ponies premedicated with buprenorphine prior to

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