B0770

Brilliant Blue G

≥80% purity (HPLC), powder

• Sinônimo(s): Acid blue 90, Coomassie Brilliant Blue G
• Fórmula empírica (Notação de Hill): C₄₇H₄₈N₃NaO₇S₂
• Número CAS: 6104-58-1
• Peso molecular: 854.02
• Número do índice de cores: 42655
• Beilstein: 5230822
• Número CE: 228-058-4
• Número MDL: MFCD00078482
• Código UNSPSC: 12171500
• ID de substância PubChem: 24891535
• NACRES: NA.47

Propriedades

• product name: Brilliant Blue G, pure
• Nível de qualidade: 200
• Ensaio: ≥80.0% (HPLC)
• forma: powder
• cor: dark violet
• solubilidade: H₂O: 1 mg/mL
• aplicação(ões): diagnostic assay manufacturing; hematology; histology
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: [Na+].CCOc1ccc(Nc2ccc(cc2)C(\c3ccc(cc3C)N(CC)Cc4cccc(c4)S([O-])(=O)=O)=C5\C=CC(\C=C5C)=[N+](\CC)Cc6cccc(c6)S([O-])(=O)=O)cc1
• InChI: 1S/C47H49N3O7S2.Na/c1-6-49(31-35-11-9-13-43(29-35)58(51,52)53)40-21-25-45(33(4)27-40)47(37-15-17-38(18-16-37)48-39-19-23-42(24-20-39)57-8-3)46-26-22-41(28-34(46)5)50(7-2)32-36-12-10-14-44(30-36)59(54,55)56;/h9-30H,6-8,31-32H2,1-5H3,(H2,51,52,53,54,55,56);/q;+1/p-1
• chave InChI: RWVGQQGBQSJDQV-UHFFFAOYSA-M

Descrição

Aplicação

Brilliant Blue G has been used for determining the urine protein concentration. It has been used for the protein band detection after SDS-PAGE (sodium dodecyl sulfate polyacrylamide gel electrophoresis). It has been used as a P2X7R (purinergic receptor) antagonist.

Ações bioquímicas/fisiológicas

Brilliant Blue G is used for staining protein(s) in polyacrylamide gels. It is also a P2X7 purinergic receptor antagonist. The receptor is mainly involved in neuroinflammatory events. In human SOD1G93A amyotrophic lateral sclerosis mouse, administration of brilliant blue G reduces body weight loss. However, it does not affect survival or motor coordination in transgenic mice.

P2X7 purinergic receptor antagonist.

Informações legais

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)