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74595

Supelco

(±)-Glycidol

analytical standard

Sinônimo(s):

(±)-Oxirane-2-methanol, 2,3-Epoxy-1-propanol, Glycerolglycide

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About This Item

Fórmula empírica (Notação de Hill):
C3H6O2
Número CAS:
556-52-5
Peso molecular:
74.08
Beilstein:
383562
Número CE:
209-128-3
Número MDL:
MFCD00005147
Código UNSPSC:
85151701
ID de substância PubChem:
329765020
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

100

densidade de vapor

2.15 (vs air)

pressão de vapor

0.9 mmHg ( 25 °C)

Ensaio

≥95.0% (GC)

temperatura de autoignição

780 °F

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

índice de refração

n20/D 1.429-1.437
n20/D 1.433 (lit.)

pb

61-62 °C/15 mmHg (lit.)

densidade

1.117 g/mL at 25 °C (lit.)

aplicação(ões)

cleaning products
cosmetics
food and beverages
personal care

formato

neat

cadeia de caracteres SMILES

OCC1CO1

InChI

1S/C3H6O2/c4-1-3-2-5-3/h3-4H,1-2H2

chave InChI

CTKINSOISVBQLD-UHFFFAOYSA-N

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Descrição geral

Glycidol is an aliphatic epoxide which may be used as a stabilizer in the manufacture of vinyl polymers, as an additive for oil and synthetic hydraulic fluids, and also as a diluent in some epoxy resins.

Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 2 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

161.6 °F

Ponto de fulgor (°C)

72 °C

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Certificados de análise (COA)

Lot/Batch Number
BCCF6002
BCCD0971
BCCC1655
BCCB1057
BCBZ3158

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Sigma-Aldrich

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Supelco

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Carcinogenicity of glycidol in F344 rats and B6C3F1 mice.
Irwin RD, et al.
Journal of Applied Toxicology, 16(3), 201-209 (1996)
NTP Toxicology and Carcinogenesis Studies of Glycidol (CAS No. 556-52-5) In F344/N Rats and B6C3F1 Mice (Gavage Studies).
National Toxicology Program and others
National Toxicology Program Technical Report Series, 374(3), 1-1 (1990)
Glycidol.
IARC monographs on the evaluation of carcinogenic risks to humans, 77, 469-486 (2000-12-02)
Hirotoshi Akane et al.
Journal of applied toxicology : JAT, 34(12), 1389-1399 (2014-01-08)
We previously found that exposure to glycidol at 1000 ppm in drinking water caused axonopathy in maternal rats and aberrations in late-stage hippocampal neurogenesis, targeting the process of neurite extension in offspring. To identify the profile of developmental neurotoxicity of
Kunio Wada et al.
Mutation research. Genetic toxicology and environmental mutagenesis, 769, 1-6 (2014-10-26)
The in vivo comet assay has been used for the evaluation of DNA damage and repair in various tissues of rodents. However, it can give false-positive results due to non-specific DNA damage associated with cell death. In this study, we
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