45706

Warfarin

PESTANAL^®, analytical standard

• Sinônimo(s): 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin, Coumafene
• Fórmula empírica (Notação de Hill): C₁₉H₁₆O₄
• Número CAS: 81-81-2
• Peso molecular: 308.33
• Beilstein: 8868198
• Número CE: 201-377-6
• Número MDL: MFCD00006854
• Código UNSPSC: 41116107
• ID de substância PubChem: 329756915
• NACRES: NA.24

Propriedades

• grau: analytical standard
• Nível de qualidade: 100
• linha de produto: PESTANAL^®
• prazo de validade: limited shelf life, expiry date on the label
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• pf: 162-164 °C (lit.)
• aplicação(ões): agriculture; environmental
• formato: neat
• cadeia de caracteres SMILES: CC(=O)CC(c1ccccc1)C2=C(O)c3ccccc3OC2=O
• InChI: 1S/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,21H,11H2,1H3
• chave InChI: PJVWKTKQMONHTI-UHFFFAOYSA-N
• Informações sobre genes: human ... VKORC1(79001)

Descrição

Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Warfarin is an anticoagulant commonly used in the prevention of thrombosis and thromboembolism. Its use is studied in stroke and pulmonary fibrosis patients among many others. It is used to study potential risks and interactions with other drugs and food.

Ações bioquímicas/fisiológicas

Warfarin consists of a racemic mixture of two active enantiomers, R- and S- forms. Warfarin is slower-acting than the common anticoagulant heparin. Warfarin inhibits the vitamin K-dependent synthesis of biologically active forms of the calcium-dependent clotting factors II, VII, IX and X. It inhibits regulatory factors protein C, protein S, and protein Z.

Atenção

Restricted to professional users. Attention − Avoid exposure − obtain special instructions before use.

Informações legais

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Pictogramas: GHS06,GHS08,GHS09
• Palavra indicadora: Danger
• Frases de perigo: H300 + H310 + H330,H360D,H372,H411
• Declarações de precaução: P202 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Classificações de perigo: Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Repr. 1A - STOT RE 1 Oral
• Órgãos-alvo: Blood
• Código de classe de armazenamento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 3