15527

Glicina

meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

• Sinônimo(s): Glicocol, Ácido aminoacético, Ácido aminoetanoico
• Fórmula linear: NH₂CH₂COOH
• Número CAS: 56-40-6
• Peso molecular: 75.07
• Beilstein: 635782
• Número CE: 200-272-2
• Número MDL: MFCD00008131
• Código UNSPSC: 12352209
• eCl@ss: 32160406
• ID de substância PubChem: 57647473
• NACRES: NA.21

Propriedades

• Nível de qualidade: 200
• Ensaio: 99-101% (based on anhydrous substance)
• forma: crystalline powder
• qualidade: meets analytical specification of Ph. Eur., BP, USP
• técnica(s): IR spectroscopy: suitable
• Impurezas: hydrolyzable substances, complies; organic volatile impurities, complies (GC); residual solvents, complies; ≤0.001% heavy metals (as Pb); ≤1.0% ninhydrin-positive substances
• resíduo de ignição: ≤0.1% (as SO₄)
• perda: ≤0.2% loss on drying, 105 °C, 2 h
• cor: white
• pH: 5.9-6.4 (20 °C, 5%)
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• pf: 240 °C (dec.) (lit.)
• solubilidade: H₂O: soluble 25 gm in 100 ml at 25 degrees c; H₂O: soluble 39.1 gm in 100 ml at 50 degrees c; alcohol: soluble 0.06 gm in 100 gm (Absolute); pyridine: soluble 164 parts; alcohol: very slightly soluble; diethyl ether: very slightly soluble
• traços de ânion: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• adequação: complies for appearance of solution; complies for reaction against H₂SO₄; in accordance for identity (IR)
• cadeia de caracteres SMILES: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• chave InChI: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Informações sobre genes: rat ... Grin2a(24409)

Descrição

Aplicação

Glycine was used for preparing platelets from whole-blood samples and study the stimulation of cytokine expression in leukocytes. It was used for biochemical and tolerance tests.

Ações bioquímicas/fisiológicas

Glycine has a pivotal role in lowering the plasma lipid levels in diabetic and obese patients by activating the CNS. During brain hypoxia glycine can stabilize the energetics disturbances in brain mitochondria. It also increases the in vitro development of porcine blastocysts when used along with glucose.

Neurotransmissor inibitório na coluna vertebral, regulador alostérico dos receptores de NMDA.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)