MABN92-AF555

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^™ 555 Conjugate

clone 20A12.1, from mouse, ALEXA FLUOR^™ 555

• Sinônimo(s): Allograft inflammatory factor 1, AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.45
• conjugado: ALEXA FLUOR^™ 555
• application: IHC
• clone: 20A12.1, monoclonal
• reatividade de espécies: rat, mouse, human
• técnica(s): immunohistochemistry: suitable

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• conjugado: ALEXA FLUOR^™ 555
• forma do anticorpo: purified antibody
• tipo de produto de anticorpo: primary antibodies
• clone: 20A12.1, monoclonal
• reatividade de espécies: rat, mouse, human
• técnica(s): immunohistochemistry: suitable
• Isotipo: IgG1κ
• nº de adesão NCBI: NP_001614
• nº de adesão UniProt: P55008
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... AIF1(199)

Descrição

Descrição geral

Allograft inflammatory factor 1 (UniProt P55008; also known as AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1) is encoded by the AIF1 (also known as G1, IBA1) gene (Gene ID 199) in human. Iba1/AIF1 is a 17 kDa interferon-gamma- (IFN-gamma-) inducible, Ca(2+)-binding EF-hand protein. Iba1/AIF1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and macrophage activation/function. It is also shown to be expressed in microglial cells in autominnume disesase models such as experimental autoimmune encephalomyelitis, neuritis and uveitis.

Imunogênio

Linear peptide corresponding to a human Iba1/AIF1 sequence.

Aplicação

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^™ 555 Conjugate is an antibody against Iba1/AIF1 for use in Immunohistochemistry.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

The unconjugated antibody (Cat. No. MABN92) is shown to be suitable also for Western blotting and immunohistochemistry applications.

Qualidade

Evaluated by Immunohistochemistry in human spleen tissue.

Immunohistochemistry Analysis: A 1:150 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.

Descrição-alvo

~17 kDa observed

forma física

Protein G Purified

Purified mouse antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Outras notas

Concentration: Please refer to lot specific datasheet.

Informações legais

ALEXA FLUOR is a trademark of Life Technologies

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable