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MAB4315

Sigma-Aldrich

Anti-STRO-1 Antibody, clone STRO-1

ascites fluid, clone STRO-1, Chemicon®

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

mouse

Nível de qualidade

100

forma do anticorpo

ascites fluid

tipo de produto de anticorpo

primary antibodies

clone

STRO-1, monoclonal

reatividade de espécies

human, primate

fabricante/nome comercial

Chemicon®

técnica(s)

flow cytometry: suitable
immunofluorescence: suitable

entrada

sample type mesenchymal stem cell(s)

Isotipo

IgM

Condições de expedição

dry ice

modificação pós-traducional do alvo

unmodified

Categorias relacionadas

Descrição geral

STRO-1 is a cell surface protein expressed by bone marrow stromal cells and erythroid precursors. The frequency of colony forming units fibroblasts (CFU-F) was enriched 100-fold in the STRO-1+/Glycophorin A- population from bone marrow cells. The subset of marrow cells that expresses the STRO-1 antigen is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts, and chondrocytes.

Especificidade

Recognizes a cell surface antigen expressed by bone marrow stromal cells and stromal precursors. STRO-1 binds to approximately 10% of bone marrow mononuclear cells, greater than 95% of which are nucleated erythroid precursors.

Imunogênio

CD34+ bone marrow cells

Aplicação

Detect STRO-1 using this Anti-STRO-1 Antibody, clone STRO-1 validated for use in FC & IF.

Nota de análise

Control
Bone marrow cultures

Informações legais

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

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Byung Cheol Kim et al.
Journal of biomedical research, 33(2), 122-130 (2019-04-24)
Despite their potential applications in future regenerative medicine, periodontal ligament stem cells (PDLSCs) are difficult to obtain in large amounts from patients. Therefore, maintaining stemness while expanding the cell numbers for medical use is the key to transitioning PDLSCs from
Carol Po Ying Lau et al.
International journal of oncology, 42(2), 437-443 (2012-12-12)
Giant cell tumor of bone (GCT) is a destructive neoplasm of uncertain etiology that affects the epiphyseal ends of long bones in young adults. GCT stromal cells (GCTSCs) are the primary neoplastic cells of this tumor and are the only
Multipotent properties of myofibroblast cells derived from human placenta.
Strakova, Z; Livak, M; Krezalek, M; Ihnatovych, I
Cell and Tissue Research null
Yiping Fan et al.
PloS one, 5(12), e14421-e14421 (2011-01-05)
Mammary stem cells have been extensively studied as a system to delineate the pathogenesis and treatment of breast cancer. However, research on mammary stem cells requires tissue biopsies which limit the quantity of samples available. We have previously identified putative
Liuhua Zhou et al.
PloS one, 10(2), e0117644-e0117644 (2015-02-24)
Autologous endothelial progenitor cells (EPCs) might be alternative angiogenic cell sources for vascularization of tissue-engineered bladder, while isolation and culture of EPCs from peripheral blood in adult are usually time-consuming and highly inefficient. Recent evidence has shown that EPCs also
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Frequently asked questions about mesenchymal stem cells including MSC derivation, expansion, differentiation and allogenic stem cell therapy.

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