MAB3502-I

Anti-Angiotensin Converting Enzyme Antibody, clone 2E2

culture supernatant, clone 2E2, from mouse

• Sinônimo(s): Angiotensin-converting enzyme, ACE, Dipeptidyl carboxypeptidase I, Kininase II, CD143
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• forma do anticorpo: culture supernatant
• tipo de produto de anticorpo: primary antibodies
• clone: 2E2, monoclonal
• reatividade de espécies: rat
• reatividade da espécie (prevista por homologia): human (immunogen homology)
• técnica(s): western blot: suitable
• Isotipo: IgG1
• nº de adesão NCBI: NP_000780
• nº de adesão UniProt: P12821
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... ACE(1636)

Descrição

Descrição geral

Angiotensin-converting enzyme (ACE) is a zinc-metallopeptidase belonging to the peptidase M2 family. It catalyzes the conversion of angiotensin I to angiotensin II and the degradation of bradykinin, which increases the vasoconstrictive effects of angiotensin. The Angiotensin-converting enzyme plays an important role in maintaining cardiac function and vascular tone. It is highly expressed in the heart, lung, kidney, gastrointestinal system, and prostate. Defects in the Angiotensin-converting may contribute cardiac disease; and renal tubular dysgenesis, a condition characterized by persistent fetal anuria and perinatal death.

Imunogênio

Human Angiotensin Converting Enzyme.

Aplicação

Anti-Angiotensin Converting Enzyme Antibody, clone 2E2.

Qualidade

Evaluated by Western Blot in rat Angiotensin Converting Enzyme.

Western Blot Analysis: A 1:2,000 dilution of this antibody detected rat Angiotensin Converting Enzyme in WB.

Descrição-alvo

~180 kDa observed. The calculated molecular weight is 150 kDa; however, this protein is known to be glycolsylated.

Ligação

Replaces: MAB3502

forma física

Mouse monoclonal IgG1 cultured supernatant without preservatives.

Nota de análise

Control
Rat Angiotensin Converting Enzyme

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable