AB2265

Anti-VPAC1 Antibody

from rabbit, purified by affinity chromatography

• Sinônimo(s): Vasoactive intestinal polypeptide receptor 1, Pituitary adenylate cyclase-activating polypeptide type II receptor, vasoactive intestinal peptide/pituitary adenylate cyclase activating peptide receptor 1
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• purificado por: affinity chromatography
• reatividade de espécies: mouse, human, rat
• técnica(s): immunohistochemistry: suitable (paraffin); western blot: suitable
• nº de adesão NCBI: NP_035833
• nº de adesão UniProt: P97751
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... VIPR1(7433)

Descrição

Descrição geral

The vasoactive intestinal peptide/pituitary adenylate cyclase activating peptide receptor 1 (VPAC1) is a member of a class II subfamily of G-protein-coupled receptors and has a high affinity for vasoactive intestinal peptide (VIP). VPAC1 has been associated with many different lung cancer cell lines. VPAC1 is thought to be activated by FXR and may contribute to the regulation of bile secretion to protect against gallstone disease. VPAC1 could be used to regulate VIPs and, in turn, inhibit breast cancer growth. VPAC1 has also been implicated in regulation of the anti-inflammatory effects of VIP.

Especificidade

This antibody recognizes VPAC1 at the cytoplasmic domain.

Imunogênio

Epitope: Cytoplasmic domain

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of VPAC1.

Aplicação

Anti-VPAC1 Antibody detects level of VPAC1 & has been published & validated for use in IH(P) & WB.

Immunohistochemistry Analysis: 1:500 dilution from a previous lot detected VPAC1 in ovarian carcinoma tissue.

Research Category
Neuroscience

Research Sub Category
Hormones & Receptors

Qualidade

Evaluated by Western Blot in SK-OV-3 cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected VPAC1 on 10 µg of SK-OV-3 cell lysate.

Descrição-alvo

~52 kDa observed. Multiple molecular weights of VPAC1 may be due to glycosylation. (Fabre, C, et al. (1993). Peptides. 14:483-489.)

forma física

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Nota de análise

Control
SK-OV-3 cell lysate

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable