8.52124

Fmoc-Lys(Alloc)-OH

≥98.0% (HPLC), for peptide synthesis, Novabiochem^®

• Sinônimo(s): Fmoc-Lys(Alloc)-OH
• Fórmula empírica (Notação de Hill): C₂₅H₂₈N₂O₆
• Número CAS: 146982-27-6
• Peso molecular: 452.50
• Número MDL: MFCD00190872
• Código UNSPSC: 12352209
• NACRES: NA.22

Propriedades

• Nome do produto: Fmoc-Lys(Alloc)-OH, Novabiochem^®
• Nível de qualidade: 200
• linha de produto: Novabiochem^®
• Ensaio: ≥96.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• Formulário: powder
• adequação da reação: reaction type: Fmoc solid-phase peptide synthesis
• fabricante/nome comercial: Novabiochem^®
• pf: 87-91 °C
• aplicação(ões): peptide synthesis
• grupo funcional: amine
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: N([C@@H](CCCCNC(=O)OCC=C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
• InChI: 1S/C25H28N2O6/c1-2-15-32-24(30)26-14-8-7-13-22(23(28)29)27-25(31)33-16-21-19-11-5-3-9-17(19)18-10-4-6-12-20(18)21/h2-6,9-12,21-22H,1,7-8,13-16H2,(H,26,30)(H,27,31)(H,28,29)/t22-/m0/s1
• chave InChI: OJBNDXHENJDCBA-QFIPXVFZSA-N

Descrição

Descrição geral

Orthogonally-protected building block for the synthesis of branched and cyclic peptides and peptides modified at the Lys side chain by Fmoc SPPS. The Alloc group can be selectively removed in the presence of standard Fmoc- and t-butyl-based protecting groups by treatment with Pd(Ph₃P)₄/CHCl₃/AcOH/NMM.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Guide to Selection of Orthogonally -Protected Building Blocks for Fmoc SPPS

Ligação

Replaces: 04-12-1305

Nota de análise

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Optical rotation α 25/D (c=1 in DMF): -13.5 - -11.0 °
Purity (TLC(157A)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 96.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informações legais

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable