8.18043

Trifluoromethanesulfonic anhydride

for synthesis

• Sinônimo(s): Trifluoromethanesulfonic anhydride
• Fórmula linear: (CF₃SO₂)₂O
• Número CAS: 358-23-6
• Peso molecular: 282.14
• Número MDL: MFCD00000408
• Código UNSPSC: 12352106
• Número do índice EC: 206-616-8
• NACRES: NA.22

Propriedades

• Nível de qualidade: 200
• Ensaio: ≥99.0% (acidimetric)
• Formulário: liquid
• potência: 1012 mg/kg LD₅₀, oral (Rat)
• densidade: 1.71 g/cm³ at 20 °C
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: FC(F)(F)[S](=O)(=O)O[S](=O)(=O)C(F)(F)F
• InChI: 1S/C2F6O5S2/c3-1(4,5)14(9,10)13-15(11,12)2(6,7)8
• chave InChI: WJKHJLXJJJATHN-UHFFFAOYSA-N

Descrição

Aplicação

• Electrophilic activation using trifluoromethanesulfonic anhydride: This method is utilized for transformations of amides, sulfoxides, and phosphorus oxides through nucleophilic trapping, highlighting its versatility in organic synthesis (Huang and Kang, 2022).
• Triflic anhydride in organic synthesis: A comprehensive review of triflic anhydride′s roles, focusing on its application across various organic transformations (Qin, Cheng, and Jiao, 2023).
• Synthesis of nitriles: Employing trifluoromethanesulfonic anhydride for converting aldoximes to nitriles under mild conditions, showcasing an innovative application in nitrile synthesis (Uludag, 2020).
• Hydrotrifluoromethylthiolation of alkenes: Uses trifluoromethanesulfonic anhydride for the hydrotrifluoromethylthiolation of unactivated alkenes and alkynes, expanding the utility of this reagent in radical reactions (Ouyang, Xu, and Qing, 2019).
• Low-cost trifluoromethylation reagent: Discusses the economic benefits and wide-ranging applications of trifluoromethanesulfonic anhydride in trifluoromethylation processes (Ouyang, Xu, and Qing, 2018).

Nota de análise

Assay (acidimetric): ≥ 99.0 %
Density (d 20 °C/ 4 °C): 1.715 - 1.720
Identity (IR): passes test

Informações de segurança

• Pictogramas: GHS03,GHS05,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H272 - H302 - H314 - H335
• Declarações de precaução: P210 - P220 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 4 Oral - Eye Dam. 1 - Ox. Liq. 2 - Skin Corr. 1B - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 5.1B - Oxidizing hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): not determined
• Ponto de fulgor (°C): not determined