341274-M

Factor H, Human

Factor H, Human, is a single-chain multi-functional glycoprotein that regulates formation and function of complement C3 and C5 convertase enzymes.

• Sinônimo(s): β _1H Globulin, β_1H Globulin
• Código UNSPSC: 12352202
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥95% (SDS-PAGE)
• Formulário: liquid
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze; avoid repeated freeze/thaw cycles
• Impurezas: IgG, IgA, IgM, Factor I, Factor B, Factor P, C3, C4, or albumin, trace (Ouchterlony)
• temperatura de armazenamento: −70°C

Descrição

Descrição geral

Native factor H from human serum. Single-chain multi-functional glycoprotein present in normal human serum at about 500 µg/ml. Regulates formation and function of complement C3 and C5 convertase enzymes. A C3b-binding protein that does not exhibit enzymatic activity. Regulatory activity is attributed to its ability to recognize and bind to C3b fragments.

Advertência

Toxicity: Standard Handling (A)

forma física

In PBS, pH 7.2.

Nota de preparo

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstituição

Following initial thaw, aliquot and freeze (-70°C).

Outras notas

Zipfel, P.F., et al. 1999. Immunopharmacology 42, 53.
Pangburn, M.K. and Muller-Eberhard, H.J. 1984. Springer Semin. Immunopathol. 7, 163.
Fearon, D.T. and Austen, K.F. 1977. Proc. Natl. Acad. Sci. USA 74, 1683.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable