14-746M-M

Src (1-530) Protein, active, 250 µg

Active, N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells. For use in Kinase Assays.

• Código UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

Propriedades

• fonte biológica: human
• Nível de qualidade: 100
• recombinante: expressed in baculovirus infected Sf21 cells
• peso molecular: M_w 61.7 kDa
• fabricante/nome comercial: Upstate^®
• técnica(s): activity assay: suitable (kinase)
• nº de adesão GenBank: K03218
• nº de adesão UniProt: P05480 (mouse); P12931; Q9WUD9 (rat)
• Informações sobre genes: human ... SRC(6714)

Descrição

Descrição geral

N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells.

Product Source: Expressed by baculovirus in Sf21 insect cells.

The mutant form of Src (Src, 1-530) has been identified in cases of advanced colon cancer. This truncating mutation generates an open active form of Src that has been found to be transforming, tumorigenic and metastasis promoting.

Aplicação

Research Category
Metabolism

Research Sub Category
Cardiovascular Disease

Metabolic Disorders

Ações bioquímicas/fisiológicas

Protein Target: Src

Target Sub-Family: TK

Embalagem

Also available in 10 μg size (cat#14-746) and in bulk (cat# 14-746-K).

forma física

50mM Tris-HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution

Ni²⁺/NTA-agarose

Armazenamento e estabilidade

6 months at -70°C from date of shipment.

Outras notas

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Informações legais

GenBank is a registered trademark of United States Department of Health and Human Services

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H317
• Declarações de precaução: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Classificações de perigo: Skin Sens. 1
• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable