1.00886

Ethyl 4-hydroxybenzoate sodium salt

EMPROVE^® ESSENTIAL, Ph. Eur., BP, NF

• Sinônimo(s): Ethyl 4-hydroxybenzoate sodium salt, p-Hydroxybenzoic acid ethyl ester sodium salt, Ethylparaben sodium salt
• Fórmula empírica (Notação de Hill): C₉H₉NaO₃
• Número CAS: 35285-68-8
• Peso molecular: 188.16
• Código UNSPSC: 12352108
• Número do índice EC: 252-487-6

Propriedades

• Agency: BP; NF; Ph. Eur.
• Nível de qualidade: 500
• linha de produto: EMPROVE^® ESSENTIAL
• forma: solid
• pH: 10 (20 °C, 1 g/L in H₂O)
• pb: 297 °C/1013 hPa (free ester,decomposition)
• pf: >115 °C (free ester)
• temperatura de transição: flash point 121 °C
• solubilidade: 1000 g/L
• aplicação(ões): liquid formulation; ophthalmics; pharmaceutical
• temperatura de armazenamento: 15-25°C
• InChI: 1S/C9H10O3.Na/c1-2-12-9(11)7-3-5-8(10)6-4-7;/h3-6,10H,2H2,1H3;/q;+1/p-1
• chave InChI: QYNMSPKSYXPZHG-UHFFFAOYSA-M

Descrição

Descrição geral

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Aplicação

Ethyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or propyl 4-hydroxybenzoate. The sodium salt provides improved solubility in water compared to standard ethyl 4-hydroxybenzoate.

Informações legais

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Pictogramas: GHS05
• Palavra indicadora: Danger
• Frases de perigo: H318
• Declarações de precaução: P280 - P305 + P351 + P338
• Classificações de perigo: Eye Dam. 1
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 249.8 °F
• Ponto de fulgor (°C): 121 °C