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Merck
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Key Documents

O-008

Supelco

Oxycodone-D6 solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (Notação de Hill):
C18H15NO4D6
Número CAS:
Peso molecular:
321.40
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24

grau

certified reference material

forma

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

embalagem

ampule of 1 mL

fabricante/nome comercial

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentração

1.0 mg/mL in methanol

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicação(ões)

forensics and toxicology

formato

single component solution

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

[2H]C([2H])([2H])Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O)C([2H])([2H])[2H]

InChI

1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,13,16,21H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1/i1D3,2D3

chave InChI

BRUQQQPBMZOVGD-UKHJWGAOSA-N

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Descrição geral

A stable-labeled internal standard suited for quantitation of oxycodone levels in urine, serum, or plasma by LC/MS or GC/MS for urine drug testing, clinical toxicology, forensic analysis, or isotope dilution methods. Oxycodone is a semi-synthetic opioid analgesic sold under many trade names including OxyContin® and Percocet® for treatment of moderate to severe pain. Oxycodone is also sold illicitly under street names such as "Roxies," "Blues," and "Perks".

Aplicação


  • Oxycodone-D₆ as an isotopic standard: Oxycodone-D₆ is employed extensively as a high-quality isotopic standard in analytical chemistry, particularly in mass spectrometry. This application is crucial for ensuring accuracy and precision in the quantification of oxycoDonein various biological matrices, enhancing drug monitoring and forensic analyses.

  • Stable isotope-labeled oxycoDonefor pharmacokinetic studies: Researchers use Oxycodone-D₆ to investigate the pharmacokinetics of oxycodone, including its absorption, distribution, metabolism, and excretion. The use of this stable isotope-labeled compound allows for more precise tracking of drug metabolites, contributing significantly to the understanding of drug behavior in the human body.

  • Oxycodone-D₆ in metabolite analysis: The deuterated form of oxycoDoneis critical in metabolite profiling studies. It serves as an internal standard that facilitates the identification and quantification of oxycoDonemetabolites, thereby aiding in the exploration of metabolic pathways and potential drug interactions.

  • Use in analytical standard development for biochemistry research: Oxycodone-D₆ solution is integral to developing robust analytical methods for drug testing and research. Its stability and reliability make it a preferred choice for validating new analytical techniques in biochemistry labs.

  • Investigation of opioid receptor binding assays: This compound is utilized in studies exploring opioid receptor interactions, aiding in the development of targeted therapies for pain management. Oxycodone-D₆ helps in understanding the binding efficiency and pharmacodynamics of opioids at the molecular level.

Informações legais

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
OxyContin is a registered trademark of Purdue Pharma L.P.
Percocet is a registered trademark of Endo Pharmaceuticals Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órgãos-alvo

Eyes

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

49.5 °F - closed cup

Ponto de fulgor (°C)

9.7 °C - closed cup


Certificados de análise (COA)

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