K-004

Ketoconazole solution

2.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Fórmula empírica (Notação de Hill): C₂₆H₂₈Cl₂N₄O₄
• Número CAS: 65277-42-1
• Peso molecular: 531.43
• Número MDL: MFCD00865612
• Código UNSPSC: 41116107
• NACRES: NA.24

Propriedades

• grau: certified reference material
• Nível de qualidade: 300
• Formulário: liquid
• Características: (Snap-N-Spike^®)
• embalagem: ampule of 1 mL
• fabricante/nome comercial: Cerilliant^®
• concentração: 2.0 mg/mL in methanol
• técnica(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• aplicação(ões): clinical testing
• Formato: single component solution
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: ClC1=C(C=CC(Cl)=C1)[C@@]2(O[C@@H](COC3=CC=C(N4CCN(C(C)=O)CC4)C=C3)CO2)CN5C=NC=C5
• InChI: 1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1
• chave InChI: XMAYWYJOQHXEEK-ZEQKJWHPSA-N

Descrição

Descrição geral

Ketoconazole, sold under trade names such as Nizoral^®, Sebizole, Ketomed, and Fungarest, is an antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. Ketoconazole is routinely assigned therapeutic drug monitoring due to its high toxicity and narrow therapeutic range. This Certified Spiking Solution^® is suitable as starting material for calibrators, controls, or linearity standards for therapeutic drug monitoring or clinical and diagnostic testing of ketoconazole in patient blood, serum, or plasma samples by HPLC or LC-MS/MS.

Informações legais

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Nizoral is a registered trademark of Johnson & Johnson

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Pictogramas: GHS02,GHS06,GHS08
• Palavra indicadora: Danger
• Frases de perigo: H225,H301 + H311 + H331,H370
• Declarações de precaução: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Classificações de perigo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Órgãos-alvo: Eyes
• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): 49.5 °F - closed cup
• Ponto de fulgor (°C): 9.7 °C - closed cup