860461P

N-C12-desoxymethylsphinganine

N-lauroyl-1-desoxymethylsphinganine (m17:0/12:0), powder

• Sinônimo(s): N-dodecanoyl-1-desoxymethylsphinganine (m17:0/12:0); N-C12-1-desoxyMeDHCer; 110959
• Fórmula empírica (Notação de Hill): C₂₉H₅₉NO₂
• Número CAS: 1246298-41-8
• Peso molecular: 453.78
• Código UNSPSC: 12352211
• NACRES: NA.25

Propriedades

• Ensaio: >99% (TLC)
• forma: powder
• embalagem: pkg of 1 × 1 mg (860461P-1mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand 860461P
• tipo de lipídio: sphingolipids; bioactive lipids
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C

Descrição

Descrição geral

Commonly referred to as 1-desoxymethyldihydroceramide (1-desoxyMeDHCer), this product is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-desoxyMeDHCer is not clearly understood at this time.

N-C12-desoxymethylsphinganine commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism.

Ações bioquímicas/fisiológicas

Ceramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of desoxymethylsphinganine (N-acylsphinganines (dihydroceramides)) levels and accumulation of sphinganine (Sa). Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis.

Embalagem

5 mL Amber Glass Screw Cap Vial (860461P-1mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3