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Key Documents

810175P

Avanti

18:1-06:0 NBD PA

Avanti Polar Lipids

Sinônimo(s):

1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphate (ammonium salt)

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About This Item

Fórmula empírica (Notação de Hill):
C33H56N5O11P
Número CAS:
Peso molecular:
729.80
Código UNSPSC:
12352211
NACRES:
NA.25

Ensaio

>99% (TLC)

forma

powder

embalagem

pkg of 5 × 2 mg (810175P-10mg)

fabricante/nome comercial

Avanti Polar Lipids

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

Categorias relacionadas

Descrição geral

Phosphatidic acid (PA) is an amphipathic lipid containing a polar head group and two long hydrophobic acyl chains. PA is an anionic and a membrane structural lipid. It acts as a parent compound for more complex membrane phospholipids.

Aplicação

18:1-06:0 NBD PA may be used for study the effects of NBD-PA induced vesiculation on epidermal growth factor receptor (EGFR) endocytosis in mammalian cells and the co-localization of fluorescently-labeled poly(A)-specific ribonuclease (PARN) with the NBD-tagged PA that outlines the close proximity phospholipase D (PLD2) and PARN.

Ações bioquímicas/fisiológicas

Phosphatidic acid (PA) is a bioactive lipid and a secondary messenger. PA reacts with water and other phospholipids to produce lipid bilayers and multicomponent bilayers respectively.

Embalagem

5 mL Amber Glass Screw Cap Vial (810175P-10mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids


Certificados de análise (COA)

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Lipid second messengers and Receptors
Encyclopedia of Endocrine Diseases, 77(3), 329-334 (2004)
Bioactive Lipids
An Introduction to Biological Membranes, , number=(, pages=), 453-478 (2016)
Taylor E Miller et al.
Biology open, 6(2), 176-186 (2016-12-25)
The removal of mRNA transcript poly(A) tails by 3'→5' exonucleases is the rate-limiting step in mRNA decay in eukaryotes. Known cellular deadenylases are the CCR4-NOT and PAN complexes, and poly(A)-specific ribonuclease (PARN). The physiological roles and regulation for PARN is
A Chauhan et al.
Neurochemical research, 25(3), 423-429 (2000-04-13)
Fibrillar amyloid beta-protein (Abeta) is the major protein of amyloid plaques in the brains of patients with Alzheimer's disease (AD). The mechanism by which normally produced soluble Abeta gets fibrillized in AD is not clear. We studied the effect of
Karen M Henkels et al.
Oncotarget, 7(30), 47002-47017 (2016-06-04)
The intracellular concentration of the mitogen phosphatidic acid (PA) must be maintained at low levels until the need arises for cell proliferation. How temporal and spatial trafficking of PA affects its target proteins in the different cellular compartments is not

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