810122P
Avanti
14:0-06:0 NBD PC
Avanti Research™ - A Croda Brand 810122P, powder
Sinônimo(s):
1-myristoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine
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About This Item
Fórmula empírica (Notação de Hill):
C34H58N5O11P
Número CAS:
Peso molecular:
743.83
Código UNSPSC:
12352211
NACRES:
NA.25
Produtos recomendados
Ensaio
>99% (TLC)
Formulário
powder
embalagem
pkg of 1 × 1 mg (810122P-1mg)
pkg of 5 × 1 mg (810122P-5mg)
fabricante/nome comercial
Avanti Research™ - A Croda Brand 810122P
Condições de expedição
dry ice
temperatura de armazenamento
−20°C
Descrição geral
Phosphatidylcholine (PC) is the most abundant phospholipid in eukaryotes and prime metabolite of glycerolipid metabolism. It is a vital component of the mucosal layer of the colon. NBD PC is a fluorophore with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) labeled to the phosphatidylcholine.
Aplicação
14:0-06:0 NBD PC may be used as a fluorescent marker in the preparation of hyaluronan (HA)-phospholipid medium for tribological studies against live cartilage. It might also be used as a substrate for type IV P-type ATPases (P4-ATPases), in the directed evolution approach to examine the molecular mechanisms of substrate backbone discrimination.
Ações bioquímicas/fisiológicas
7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) functions as a fluorescent lipid analog, used in biological membranes to study various cellular processes. It plays a vital role as a strong bilayer-forming lipid.
Embalagem
5 mL Amber Glass Screw Cap Vial (810122P-1mg)
5 mL Amber Glass Screw Cap Vial (810122P-5mg)
Informações legais
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Código de classe de armazenamento
11 - Combustible Solids
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Teresa Veselack et al.
Lubricants (Basel, Switzerland), 6(1) (2018-03-13)
Pre-clinical testing of hemiarthroplasty devices requires that the tribological conditions present in vivo with live cartilage be closely duplicated. A current limitation in the tribological testing of live cartilage involves the use of cell-culture media as lubricant. to develop and
Bartholomew P Roland et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(31), E4460-E4466 (2016-07-20)
Phospholipid flippases in the type IV P-type ATPase (P4-ATPases) family establish membrane asymmetry and play critical roles in vesicular transport, cell polarity, signal transduction, and neurologic development. All characterized P4-ATPases flip glycerophospholipids across the bilayer to the cytosolic leaflet of
Yi-Chih Lin et al.
Nature communications, 11(1), 230-230 (2020-01-15)
Annexins are abundant cytoplasmic proteins, which bind to membranes that expose negatively charged phospholipids in a Ca2+-dependent manner. During cell injuries, the entry of extracellular Ca2+ activates the annexin membrane-binding ability, subsequently initiating membrane repair processes. However, the mechanistic action of
Wei Zong et al.
Langmuir : the ACS journal of surfaces and colloids, 34(23), 6874-6886 (2018-05-20)
The success of nanoparticulate formulations in drug delivery depends on various aspects including their toxicity, internalization, and intracellular location. Vesicular assemblies consisting of phospholipids and amphiphilic block copolymers are an emerging platform, which combines the benefits from liposomes and polymersomes
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