T342254

5-(azidomethyl)-2′-deoxyuridine (AmdU)

• Sinônimo(s): 5-(azidomethyl)-1-((2R,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, AmdU
• Fórmula empírica (Notação de Hill): C₁₀H₁₃N₅O₅
• Peso molecular: 283.24
• Número MDL: MFCD28053582
• Código UNSPSC: 12352200
• ID de substância PubChem: 329826764

Propriedades

• Formulário: solid
• Nível de qualidade: 100
• cadeia de caracteres SMILES: O[C@@H]1[C@@H](CO)O[C@@H](N2C(NC(C(CN=[N+]=[N-])=C2)=O)=O)C1
• InChI: 1S/C10H13N5O5/c11-14-12-2-5-3-15(10(19)13-9(5)18)8-1-6(17)7(4-16)20-8/h3,6-8,16-17H,1-2,4H2,(H,13,18,19)/t6-,7+,8+/m0/s1
• chave InChI: JKSAKMHLWMCADM-XLPZGREQSA-N

Descrição

Aplicação

5-(Azidomethyl)-2′-deoxyuridine (AmdU) exhibits good chemical stability and the ability to metabolically label cellular DNA. Following its incorporation into cellular DNA by endogenous enzymes, AmdU can be detected using both copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC) reactions.

An Azide-Modified Nucleoside for Metabolic Labeling of DNA

Outras notas

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Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable