CPGG-502

Anionic PEGylated Liposomes

DOPC:Chol:DOPG:DOPE-PEG(2000) (60:30:5:5 molar ratio 10mM)

• Código UNSPSC: 12352211
• NACRES: NA.25

Propriedades

• Nível de qualidade: 100
• composição: Phosphate buffered saline
• concentração: 10 mM
• Impurezas: 30 mol % Cholesterol ; 5 mol % DOPE-PEG2000; 5 mol % DOPG; 60 mol % DOPC
• tamanho de partícula: 100 nm
• pH: 7.4

Descrição

Descrição geral

Poly(ethylene glycol) (PEG) is commonly added to liposomes to improve stability, hydrophilicity and enhance circulation time. Anionic PEGylated liposomes protect liposomes from circulating proteins, improving their plasma clearance and enhancing their therapeutic effects. In addition, anionic liposomes demonstrate greater stability in solution, lead to lower aggregation when compared to neutral liposomes, and have increased endocytosis when compared with cationic and neutral liposomes.

Aplicação

Drug delivery
Lipid-protein interactions

Armazenamento e estabilidade

Liposomes should never be frozen. Liposomes should be stored in the dark at 4°C, except when brought to room temperature for brief periods prior to use.

Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.

Informações legais

Cellsome is a trademark of Encapsula NanoSciences

Product of Encapsula Nanosciences

Exoneração de responsabilidade

For research use only

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable