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700312

Sigma-Aldrich

Iron oxide(II,III), magnetic nanoparticles solution

10 nm avg. part. size, 5 mg/mL in toluene

Sinônimo(s):

Magnetic iron oxide nanocrystals, Magnetite, Superparamagnetic iron oxide nanoparticles

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About This Item

Fórmula empírica (Notação de Hill):
Fe3O4
Número CAS:
Peso molecular:
231.53
Número MDL:
Código UNSPSC:
12352302
ID de substância PubChem:
NACRES:
NA.23

forma

nanoparticles
solution

Nível de qualidade

concentração

5 mg/mL in toluene

magnetização

>45 emu/g (at ambient temperature under 4500 Oe)

Tamanho médio da partícula

10 nm

tamanho de partícula

9-11 nm (TEM; conforms)

densidade

0.865 g/mL at 25 °C

cadeia de caracteres SMILES

O=[Fe].O=[Fe]O[Fe]=O

InChI

1S/3Fe.4O

chave InChI

SZVJSHCCFOBDDC-UHFFFAOYSA-N

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Descrição geral

Iron oxide(II,III), magnetic nanoparticles solution (Fe3O4) is an organic solvent dispersed nanoparticle solution, which can be synthesized by the thermal decomposition of iron acetylacetonate in 2-pyrrolidone. It is majorly used in biomedical applications due to its magnetic properties, particle size, and surface properties.
It contains <1.0% oleic acid stabilizing ligands.
Concentration 5mg/ml includes total weight nanocrystals plus ligands.

Aplicação

Fe3O4 can be used in the targeting and imaging of tumor cells for cancer therapy-based applications. It may also be used in the separation of tumor cells from fresh whole blood. It can also be used as an effective material in drug delivery systems and magnetic resonance imaging (MRI).

Palavra indicadora

Danger

Classificações de perigo

Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

Órgãos-alvo

Central nervous system

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

45.0 °F

Ponto de fulgor (°C)

7.2 °C

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Nonpolymeric coatings of iron oxide colloids for biological use as magnetic resonance imaging contrast agents
Portet D, et al.
Journal of Colloid and Interface Science, 238(1), 37-42 (2001)
Superparamagnetic nanoparticles for biomedical applications: possibilities and limitations of a new drug delivery system
Neuberger T, et al.
Journal of magnetism and magnetic materials, 293(1), 483-496 (2005)
Antibody conjugated magnetic iron oxide nanoparticles for cancer cell separation in fresh whole blood
Xu H, et al.
Biomaterials, 32(36), 9758-9765 (2011)
Targeted magnetic iron oxide nanoparticles for tumor imaging and therapy
Peng X, et al.
International journal of nanomedicine, 3(3), 311-311 (2008)
Synthesis of Fe3O4 nanoparticles with various sizes and magnetic properties by controlled hydrolysis
Iida H, et al.
Journal of Colloid and Interface Science, 314(1), 274-280 (2007)

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