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Sigma-Aldrich

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide

≥97.0% (T)

Sinônimo(s):

N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide, EDC, WSC

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About This Item

Fórmula empírica (Notação de Hill):
C8H17N3
Número CAS:
1892-57-5
Peso molecular:
155.24
Beilstein:
507429
Número CE:
217-579-2
Número MDL:
MFCD00044916
Código UNSPSC:
12352116
ID de substância PubChem:
57649895

Nível de qualidade

100

Ensaio

≥97.0% (T)

forma

liquid

adequação da reação

reaction type: Coupling Reactions

índice de refração

n20/D 1.461

densidade

0.877 g/mL at 20 °C (lit.)

aplicação(ões)

peptide synthesis

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CCN=C=NCCCN(C)C

InChI

1S/C8H17N3/c1-4-9-8-10-6-5-7-11(2)3/h4-7H2,1-3H3

chave InChI

LMDZBCPBFSXMTL-UHFFFAOYSA-N

Categorias relacionadas

Descrição geral

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide is commonly used in combination with N-hydroxysuccinimide (NHS) in carbodiimide coupling reaction to activate carboxyl group for coupling with amines to form amides.

Aplicação

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide has been used for the surface functionalization of graphene quantum dots (GQDs) employed as sensing probes in Janus micromotors to detect enterobacterial contamination. It has also been used for the activation of folic acid, prior to its conjugation on silica nanoparticles.

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1A - STOT RE 2 Oral

Código de classe de armazenamento

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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SENSITIVE MONITORING OF ENTEROBACTERIAL CONTAMINATION OF FOOD USING SELF-PROPELLED JANUS MICROSENSORS
Pacheco M
Analytical Chemistry, 90(4), 2912-2917 (2018)
Anthony C Y Yau et al.
Scientific reports, 7(1), 14998-14998 (2017-11-10)
Mineral oils are extensively used in our daily life, in food, cosmetics, biomedicine, vaccines and in different industrial applications. However, exposure to these mineral oils has been associated with immune adjuvant effects and the development of autoimmune diseases. Here we
Ruogu Qi et al.
Nature communications, 8(1), 2166-2166 (2017-12-20)
Advanced-stage epithelial ovarian cancers are amongst the most difficult to treat tumors and have proven to be refractory to most cytotoxic, molecularly targeted, or immunotherapeutic approaches. Here, we report that nanoparticle-drug conjugates (NDCs) of monomethyl auristatin E (MMAE) significantly increase
Immobilization of laccase on polymer grafted polytetrafluoroethylene membranes for biosensor construction.
Tastan E
Talanta, 84(2), 524-530 (2011)
Michael J Taylor et al.
Journal of biomedical materials research. Part A, 107(10), 2195-2204 (2019-05-23)
Scaffolds composed of synthetic polymers such as poly(caprolactone) (PCL) are widely used for the support and repair of tissues in biomedicine. Pores are common features in scaffolds as they facilitate cell penetration. Various surface modifications can be performed to promote
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