286958
Phenylpyruvic acid
98%
Sinônimo(s):
2-Oxo-3-phenylpropanoic acid, 2-Oxo-3-phenylpropionic acid
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About This Item
Fórmula linear:
C6H5CH2COCOOH
Número CAS:
Peso molecular:
164.16
Beilstein:
2207312
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.22
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Nível de qualidade
Ensaio
98%
pf
150-154 °C (lit.)
grupo funcional
carboxylic acid
ketone
phenyl
temperatura de armazenamento
−20°C
cadeia de caracteres SMILES
OC(=O)C(=O)Cc1ccccc1
InChI
1S/C9H8O3/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5H,6H2,(H,11,12)
chave InChI
BTNMPGBKDVTSJY-UHFFFAOYSA-N
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Descrição geral
Phenylpyruvic acid reduces glucose-6-phosphate dehydrogenase activity without pre-incubation.
Aplicação
Phenylpyruvic acid was used in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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Shuhuai Yu et al.
Biotechnology letters, 36(3), 627-631 (2013-11-20)
3-Phenyllactic acid (PLA) is an antimicrobial compound with broad and effective antimicrobial activity against both bacteria and fungi. Enzymatic production of PLA can be carried out from phenylpyruvic acid by lactate dehydrogenase (LDH); however, the enzymatic reaction is accompanied by
Taiki Fujii et al.
Biochimica et biophysica acta, 1814(12), 1669-1676 (2011-06-16)
We discovered the phenyllactate (PLA)-producing fungal strain Wickerhamia fluorescens TK1 and purified phenylpyruvate reductase (PPR) from fungal cell-free extracts. The PPR used both NADPH and NADH as cofactors with more preference for the former. The enzyme reaction as well as
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Phenylketonuria is a recessive autosomal disorder that is caused by a deficiency in the activity of phenylalanine-4-hydroxylase, which converts phenylalanine to tyrosine, leading to the accumulation of phenylalanine and its metabolites phenyllactic acid, phenylacetic acid, and phenylpyruvic acid in the
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