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Documentos Principais

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13155

Sigma-Aldrich

N6-Benzyladenosine

≥99.0%

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About This Item

Fórmula empírica (Notação de Hill):
C17H19N5O4
Número CAS:
4294-16-0
Peso molecular:
357.36
Beilstein:
56815
Número CE:
224-298-9
Número MDL:
MFCD00005740
Código UNSPSC:
12352200
ID de substância PubChem:
57647065

Nível de qualidade

100

Ensaio

≥99.0%

forma

powder

pf

184-186 °C

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4ccccc4)ncnc23

InChI

1S/C17H19N5O4/c23-7-11-13(24)14(25)17(26-11)22-9-21-12-15(19-8-20-16(12)22)18-6-10-4-2-1-3-5-10/h1-5,8-9,11,13-14,17,23-25H,6-7H2,(H,18,19,20)/t11-,13-,14-,17-/m1/s1

chave InChI

MRPKNNSABYPGBF-LSCFUAHRSA-N

Informações sobre genes

human ... ADORA3(140)
rat ... Adora1(29290) , Adora2a(25369) , Adora3(25370)

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Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
BCBT6940
BCBN6914V
BCBJ0385V
1350990V
1350990

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P Mlejnek
Journal of cellular biochemistry, 83(4), 678-689 (2001-12-18)
As an extension of our recently published work (Mlejnek and Kuglík [2000] J. Cell. Biochem. 77:6-17), the role of caspases in N(6)-benzylaminopurine riboside (BAPR)-induced apotosis in HL-60 cells was evaluated in this study. Here, BAPR-induced apoptosis was accompanied by activation
P Mlejnek et al.
Journal of cellular biochemistry, 77(1), 6-17 (2000-02-19)
Treatment of HL-60 cells with micromolar concentrations of N(6)-benzyladenosine (N(6)-benzylaminopurine riboside [BAPR]) led to the occurrence of apoptosis in a concentration-dependent manner. Incubation period as short as 2 h in the presence of BAPR was sufficient for triggering irreversible changes
V Vlasáková et al.
Journal of pharmaceutical and biomedical analysis, 17(1), 39-44 (1998-06-03)
High performance liquid chromatography (HPLC) with an on-line flow-through radioactivity detector was used to monitor the metabolism of cytokinins ([3H]6-benzylaminopurine and [3H]6-benzylaminopurine riboside) after their incorporation into wheat seedlings. The production and conversion of individual metabolites was assayed within a
R G Luiten et al.
Nucleic acids research, 11(22), 8073-8085 (1983-11-25)
From in vitro protein synthesis studies and nucleotide sequence analysis it has been deduced that, unlike the major coat proteins of the hitherto studied filamentous bacterial viruses Ff (M13, fd and f1), IKe and Pf1, the major coat protein of
Petr Dolezel et al.
Toxicology in vitro : an international journal published in association with BIBRA, 24(8), 2079-2083 (2010-07-20)
Cytotoxicity of two halogen derivatives of N⁶-benzyladenosine (BAPR), N⁶-(3-iodobenzyl)-adenosine (I-BAPR) and 2-chloro-N⁶-(3-iodobenzyl)-adenosine (Cl-I-BAPR), was tested in human leukemia U937 cell line. Our results revealed that their cytotoxicity was surprisingly low. I-BAPR and also Cl-I-BAPR induced cell death with morphological and
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