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Merck

SCN11A

sodium channel, voltage-gated, type XI, alpha subunit

Sinônimos:
NAV1.9, NaN, SCN12A, SNS-2
Espécies:
ID UniProtKB:
ID do gene:
  • Human(11280) Summary: Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.[supplied by OMIM, Apr 2004]
  • Mouse(24046) sodium channel, voltage-gated, type XI, alpha
  • Rat(29701) sodium channel, voltage-gated, type XI, alpha subunit
  • cow(535956) sodium channel, voltage-gated, type XI, alpha subunit
  • sheep(101117022) sodium channel, voltage-gated, type XI, alpha subunit
  • naked mole-rat(101723747) sodium channel, voltage-gated, type XI, alpha subunit
  • Domestic Rabbit(100349709) sodium channel, voltage-gated, type XI, alpha subunit
  • domestic guinea pig(100734219) sodium channel, voltage-gated, type XI, alpha subunit
  • dog(485593) sodium channel, voltage-gated, type XI, alpha subunit
  • domestic cat(101085312) sodium channel, voltage-gated, type XI, alpha subunit

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-SCN11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-SCN11A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Monoclonal Anti-SCN11A, (C-terminal) antibody produced in mouse, clone 2B10, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
Anti-Sodium Channel NaV1.9 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reatividade de espécies
rat
Aplicação
western blot
Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse, ~1 mg/mL, clone K58/35, purified immunoglobulin,
Reatividade de espécies
mammals
Aplicação
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Blocker

Número do produto
Descrição
Espécies
Lidocaína, solid,
Espécies
human
Procaine hydrochloride, ≥97%,
Espécies
human
Procainamide hydrochloride, ≥98% (HPLC),
Espécies
human
Álcool 2,4-diclorobenzílico, 99%,
Espécies
human
Lidocaína, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human SCN11A,
Espécies
human