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Merck

PYCARD

PYD and CARD domain containing

Sinônimos:
ASC, CARD5, TMS, TMS-1, TMS1
Espécies:
ID UniProtKB:
ID do gene:
  • Human(29108) Summary: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(66824) PYD and CARD domain containing
  • Rat(282817) PYD and CARD domain containing
  • Zebrafish(57923) PYD and CARD domain containing
  • dog(489925) PYD and CARD domain containing
  • domestic cat(101088449) PYD and CARD domain containing
  • cow(282846) PYD and CARD domain containing
  • sheep(101105208) PYD and CARD domain containing
  • Goat(100861338) PYD and CARD domain containing
  • domestic guinea pig(100734858) PYD and CARD domain containing

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-ASC Antibody, clone 2EI-7, clone 2EI-7, from mouse,
Reatividade de espécies
human, mouse
Aplicação
flow cytometry
western blot
Anti-ASC antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry

western blot
Anti-ASC/TMS1 antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
western blot
Anti-PYCARD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry

western blot
Anti-ASC/TMS1 antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry

western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human PYCARD,
Espécies
human