POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
Sinônimos:
POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1
Espécies:
Human POLR2A (5430), Mouse Polr2a (20020), Rat Polr2a (363633), domestic guinea pig Polr2a (100734232), naked mole-rat Polr2a (101725588), cow POLR2A (282312), sheep POLR2A (100144762), Zebrafish polr2a (553347), dog POLR2A (479483), domestic cat POLR2A (101098500)
ID UniProtKB:
ID do gene:
- Human(5430) Summary: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
- Mouse(20020) polymerase (RNA) II (DNA directed) polypeptide A
- Rat(363633) polymerase (RNA) II (DNA directed) polypeptide A
- domestic guinea pig(100734232) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- naked mole-rat(101725588) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- cow(282312) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- sheep(100144762) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- Zebrafish(553347) polymerase (RNA) II (DNA directed) polypeptide A
- dog(479483) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- domestic cat(101098500) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
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Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-RNA Polymerase II Antibody, CTD Antibody, clone 8WG16, clone 8WG16, from mouse,
Reatividade de espécies
human, yeast
Aplicação
dot blot
immunoprecipitation (IP)
inhibition assay
western blot
immunoprecipitation (IP)
inhibition assay
western blot
Anti-phospho RNA Pol II (Ser5), clone 1H4B6 Antibody, clone 1H4B6, from rat,
Reatividade de espécies
canine, human, monkey, mouse, rat
Aplicação
ChIP
ELISA
immunocytochemistry
western blot
ELISA
immunocytochemistry
western blot
Monoclonal Anti-phospho-RNA polymerase II CTD (pSer2) antibody produced in rat, clone 3E7C7, purified from hybridoma cell culture,
Reatividade de espécies
Aplicação
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-phospho RNA Pol II (Ser2), clone 3E7C7 Antibody, clone 3E7C7, from rat,
Reatividade de espécies
canine, human, monkey, mouse, rat
Aplicação
ChIP
ELISA
immunocytochemistry
western blot
ELISA
immunocytochemistry
western blot
Anti-POLR2A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence